北京市西城区2014年麻疹疑似病例IgM抗体检测结果分析  

Analysis on the IgM Antibody Detection Results of Measles Suspected Cases in Xicheng Area of Beijing in 2014

作　　者：王宵雪[1] 胡三梅[1] 庞晶晶[1] 路燕[1] 

机构地区：[1]北京市西城区疾病预防控制中心,北京100120

出　　处：《中国初级卫生保健》2016年第2期59-62,共4页Chinese Primary Health Care

摘　　要：目的对2014年北京市西城区麻疹疑似病例进行IgM抗体检测,掌握本地区麻疹流行趋势,为进一步制定麻疹防治策略提供科学依据。方法应用酶联免疫吸附试验（ELISA）对疑似麻疹病例血清标本同时检测麻疹、风疹IgM抗体。结果2014年共检测麻疹疑似病例204例。检出麻疹IgM抗体阳性72例,阳性率为35.29%;风疹IgM抗体阳性7例,阳性率为3.43%。麻疹IgM抗体阳性年龄主要分布于31-40岁年龄组,其次是21-30岁年龄组。分别占全年麻疹IgM抗体阳性病例总数的26.39%、18.06%。麻疹流行高峰集中在3-5月份。风疹阳性年龄主要分布于21-30岁年龄组,占全年风疹IgM抗体阳性病例总数的85.71%。风疹流行高峰集中在3-4月份。麻疹IgM抗体阳性率与血清采集时间有密切关系,麻疹IgM抗体阳性率随着采样与出疹时间差的增加而出现逐渐降低趋势,85.71%（6例）的风疹IgM抗体阳性病例的出疹时间在7天以内。麻疹、风疹病例中无免疫史或免疫不详者占88.29%、92.11%。结论建议对21-40岁年龄组的重点人群进行麻疹强化免疫,提高易感人群麻疹免疫水平,同时需要加强风疹的监测和开展查漏补种工作,控制麻疹、风疹在人群中的传播。OBJECTIVE To detect IgM antibody of suspected measles cases in Xicheng District of Beijing in 2014, analyze on measles epidemiological characteristics, provide scientific basis for further work on measles control strategies. METHODS Detecting the measles, rubella IgM antibodies of suspected cases in serum samples which used enzyme linked immunosorbent assay（ELISA）. RESULTS In 2014, 204 suspected measles cases were detected. 72 cases of measles were confirmed the positive of IgM antibody, the positive rate was 35.29% ; 7 cases of rubella were confirmed the positive of IgM antibody, the positive rate was 3.43%. Tested positive for measles were mainly located in 31-40 years old of age, followed by 21-30 years old of age, which accounted for 26.39% and 18.06% respectively. Measles popular peak period was from March to May. Tested positive for rubella were mainly located in 21- 30 years old of age, which accounted for 85.71%. Rubella popular peak was from March to April. Measles and rubella IgM antibody positive rate was closely related to serum collection time. It found that positive rate of measles IgM antibody declined along with the days after rash occurrence. 6 cases of rubella positive of IgM antibody（85.71%）occurred during 7 days of rash. The measles, rubella case of no history of immunization or immunity unknown were 88.29% and 92.11% respectively. CONCLUSION Measles immunization of key population of 21-40 years old should be enhanced and improved immunization level of susceptible population. It also needed to strengthen monitoring of rubella, check the leakage of rubella antibody level and replenish rubella vaccine properly, control the transmission of measles and rubella among human.

关 键 词：麻疹 风疹 疑似病例 IGM抗体 北京 

分 类 号：R52[医药卫生—内科学]