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作 者:Chuandeng Yi Mingsen Wang Wei Jiang Derong Wang Yong Zhou Zhiyun Gong Guohua Liang Minghong Gu
出 处:《Journal of Genetics and Genomics》2015年第12期699-702,共4页遗传学报(英文版)
基 金:supported by the grants from the National Natural Science Foundation of China(Nos.31576124,31071382 and 30771210);the National Basic Research Program of China(973 Program,Nos.2010CB125904 and 2013CBA01405)
摘 要:The centromere of eukaryotic chromosomes is the crucial locus responsible for sister chromatid cohesion and for correct segregation of chromosomes to daughter cells during cell division. In the structural genomics era, centromeres represent the last frontiers of higher eukaryotic genomes because of their densely methylated, highly repetitive and, heterochromatic DNA (Hall et al., 2004). Although these functions are conserved among all eukaryotes, centromeric DNA sequences are evolving rapidly (Jiang et al., 2003).The centromere of eukaryotic chromosomes is the crucial locus responsible for sister chromatid cohesion and for correct segregation of chromosomes to daughter cells during cell division. In the structural genomics era, centromeres represent the last frontiers of higher eukaryotic genomes because of their densely methylated, highly repetitive and, heterochromatic DNA (Hall et al., 2004). Although these functions are conserved among all eukaryotes, centromeric DNA sequences are evolving rapidly (Jiang et al., 2003).
关 键 词:FISH BAC Isolation and Identification of a Functional Centromere Element in the Wild Rice Species Oryza granulata with the GG Genome
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