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出 处:《临床神经外科杂志》2015年第6期461-464,共4页Journal of Clinical Neurosurgery
摘 要:目的探讨脑室-腹腔分流术后颅内感染保守治疗的方法及效果。方法回顾性分析浙江省丽水市中心医院2005年1月~2012年12月采用保守治疗的13例脑室-腹腔分流术后颅内感染且分流功能正常患者的临床资料。治疗包括全身及鞘内应用抗生素、腰大池外引流。结果 13例患者抗感染治疗10~21 d,均治愈出院。鞘内注射抗生素无毒副作用发生,成功保留了分流管且分流功能均正常。患者出院后随访10个月~6年,均无感染复发,无分流管堵塞。结论保守治疗能够治愈分流术后颅内感染,保守治疗脑室-腹腔分流术后感染,安全可靠,避免了二次手术及其风险。Objective To explore methods and effects of conservative treatment for patients with intracranial infection after ventriculo-peritoneal (V-P) shunt. Methods The clinical data of 13 patients with intracranial infection after V-P shunt underwent by conservative treatment from January 2005 to December 2012 were analyzed retrospectively. Treatment was based on the administration of a combination of lumbar drainage, intraventricular and systemic antibiotics. Results 13 patients were cured after treated with antibiotics for 10 to 21 days, and kept functioning shunts. There was no toxicity related to intraventricular antibiotics administration. The follow-up from 10 to 72 months showed they were free from recurrent infection and shunt blockage. Conclusion The conservative management can cure patients with shunt infections, avoids surgical intervention, with its attendant risks, and is safe and reliable.
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