Synthesis and thermal stability of selenium-doped hydroxyapatite with different substitutions  

作　　者：Yonghui LIU Jun MA Shengmin ZHANG 

机构地区：[1]Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan 430074, China [2]Department of Biomedical Engineering, Huazhong University of science and Technology, Wuhan 430074, China

出　　处：《Frontiers of Materials Science》2015年第4期392-396,共5页材料学前沿（英文版）

基　　金：Acknowledgements This work was supported by the National Basic Research Program of China （Grant No. 2012CB933601） and the National Natural Science Foundation of China （Grant Nos. 51202075, 81071263 and 81461148032）.

摘　　要：Selenium （Se） plays a specific role in human health, especially for its anti- tumor effect. Incorporation of selenium into biocompatible hydroxyapatite （HAP） may endow the materials with novel characteristics. In the current work, a series of seleniumdoped hydroxyapatite （Se-HAP） nanoparticles with different SelP ratios were synthesized by a modified chemical precipitation. It was revealed that the powders with/without heattreatment were nano-sized needle-like HAP while the heat-treated samples have high crystallinity. The addition of selenium decreases the crystallinity of the synthesized apatite, and also takes a negative effect on the thermal stability of the as-prepared powders. The Se-HAP nanoparticles with Se/P molar ratio not more than 5% sintered at 900℃ can achieve good crystallinity and thermal stability.Selenium （Se） plays a specific role in human health, especially for its anti- tumor effect. Incorporation of selenium into biocompatible hydroxyapatite （HAP） may endow the materials with novel characteristics. In the current work, a series of seleniumdoped hydroxyapatite （Se-HAP） nanoparticles with different SelP ratios were synthesized by a modified chemical precipitation. It was revealed that the powders with/without heattreatment were nano-sized needle-like HAP while the heat-treated samples have high crystallinity. The addition of selenium decreases the crystallinity of the synthesized apatite, and also takes a negative effect on the thermal stability of the as-prepared powders. The Se-HAP nanoparticles with Se/P molar ratio not more than 5% sintered at 900℃ can achieve good crystallinity and thermal stability.

关 键 词：SELENIUM HYDROXYAPATITE thermal stability CRYSTALLINITY 

分 类 号：TQ174.75[化学工程—陶瓷工业] O613.52[化学工程—硅酸盐工业]