MRI不同序列对骶髂关节软骨成像的比较  

Comparative study on different sequence MRI imaging of the sacroiliac joint cartilage

作　　者：刘博[1] 史大鹏[2] 郑福增[3] 孙永强[3] 杨中杰[1] 王同明[1] 

机构地区：[1]河南省中医院放射科,河南省郑州市450002 [2]河南省人民医院影像中心,河南省郑州市450003 [3]河南省中医院骨科,河南省郑州市450002

出　　处：《中国组织工程研究》2015年第51期8223-8227,共5页Chinese Journal of Tissue Engineering Research

基　　金：河南省科技攻关计划项目(132102310159)~~

摘　　要：背景:平片及CT不能显示关节软骨的改变,磁共振虽可显示软骨,但常规序列软骨显像效果欠佳,因此若要提高MRI检出软骨病变的能力,序列的优化显得非常重要。目的:比较骶髂关节常用磁共振成像序列,筛选适合骶髂关节软骨MRI最佳成像序列。方法:对45健康志愿者分别行骶髂关节MRI自旋回波T1WI、T2WI、T1-flash-3d-water-cor、T2-me3d-cor和T2-me2d-cor和T1-se-cor-water-fil扫描,比较各个序列显示骶髂关节软骨的清晰度、内部信号变化及软骨表面缺损。结果与结论:自旋回波T1WI和T2WI序列45均显示骶髂关节软骨为一条稍高信号带,关节间隙不清;梯度回波T1-se-cor-water-fil序列45均显示两侧关节面骨皮质与髂侧软骨、骶侧软骨及软骨间隙形成的5条平行线状结构;T2-me3d-cor、T1-flash-3D-water-cor-fil序列45例受检者关节软骨为一条明亮、清晰高信号,与周围骨皮质及骨髓分界非常清晰,但骶侧、髂侧软骨不能够区分。T2-me2d-cor序列37例能显示髂侧、骶侧软骨及软骨间关节间隙,8例分辨不清;弥散成像序列仅部分层面能显示关节软骨,诸结构显示较模糊,信号强度对比不鲜明。结果说明,T1-se-cor-water-fil在关节软骨显示程度、内部信号变化和软骨表面缺损程度等方面明显优于其他序列。T1-flash-3d-water-cor、T2-me3d-cor和T2-me2d-cor对软骨表显示方面优于常规MRI序列,但不如T1-se-cor-water-fil。BACKGROUND： Plain films and CT cannot show the variation of the articular cartilages. Although MRI can show the cartilage, the conventional sequence imaging of the cartilage is ineffective. To optimize MRI sequence is very important to detect cartilage lesions. OBJECTIVE： To find the most suitable sequences for MRI imaging of sacroiliac joint cartilage. METHODS： Forty-five healthy voluntary subjects were subjected to MRI scans of the sacroiliac joint at T1 WI, T2 WI, T1-flash-3d-water-cor, T2-me3d-cor, T2-me2d-cor and T1-se-cor-water-fil. Clarity of the sacroiliac joint cartilage, internal signal changes and cartilage surface defects shown on MRI images were compared. RESULTS AND CONCLUSION： MRI images with T1 WI and T2 WI sequences displayed the sacroiliac articular cartilage as a higher signal band with vague joint space. MRI images with T1-se-cor-water-fil displayed five parallel lines between bilateral cortical bone on the joint surface and iliac cartilage, sacral cartilage and cartilagegap. MRI images with T2-me3d-cor and T1-flash-3D-water-cor-fil displayed the sacroiliac articular cartilage as a bright, clear high signal band that had clear boundaries with the surrounding cortical bone and bone marrow, but the sacral and iliac cartilage could not be distinguished. MRI images with T2-me2d-cor sequence showed iliac cartilage, sacral cartilage and joint space in 37 of 45 cases. Diffusion tensor imaging could display the articular cartilage partially with vague structure and the signal strength had no contrast. These findings indicate that T1-se-cor-water-fil is superior to other sequences to display the cartilage, internal signal and cartilage surface defects. T1-flash-3d-water-cor, T2-me3d-cor and T2-me2d-cor are better than conventional MRI sequences rather than T1-se-cor-water-fil.

关 键 词：脊柱炎 强直性 磁共振成像 软骨 关节 组织工程 组织构建 软骨组织工程 骶髂关节炎 关节软骨 强直性脊柱炎 

分 类 号：R318[医药卫生—生物医学工程]