山西省肿瘤医院住院患者人类免疫缺陷病毒感染的调查分析  

Investigation of the hospitalized patients with human immunodeficiency virus infection in Shanxi Cancer Hospital

作　　者：石砚海[1] 魏让[2] 

机构地区：[1]山西省肿瘤医院检验科,太原030013 [2]山西省肿瘤医院医学检验部,太原030013

出　　处：《肿瘤研究与临床》2015年第12期838-839,850,共3页Cancer Research and Clinic

摘　　要：目的 调查山西省肿瘤医院住院患者人类免疫缺陷病毒（HIV）感染的流行病学特征。方法 在2004年1月至2014年12月山西省肿瘤医院住院患者中共检出70例HIV阳性确诊患者，其中，经组织病理学确诊的HIV感染合并恶性肿瘤患者55例，单纯HIV感染患者15例。结果 55例HIV感染合并恶性肿瘤患者年龄7～80岁，以46～55岁年龄组患者比例高，15例单纯HIV感染患者平均年龄为35岁（7～55岁）。合并恶性肿瘤共15种，以肺癌最多，为11例（20 %），其次为肝癌、胃癌和非霍奇金淋巴瘤，均为5例（9 %）。70例HIV感染患者中，职业以农民为主，占43 %（30例），明显高于其他职业。结论 HIV感染合并恶性肿瘤患者年龄大于单纯HIV感染患者，可能与此年龄段免疫功能逐渐低下、继发机会性感染率升高或恶性肿瘤的发病率较高有关，提示随着HIV感染患者生存期的延长，恶性肿瘤发病率呈升高的趋势。Objective To investigate the epidemiological characteristics of the hospitalized patients with human immunodeficiency virus （HIV） infection in Shanxi Cancer Hospital. Methods 70 patients with HIV positive were detected in Shanxi Cancer Hospital from January 2004 to December 2014. 55 patients with HIV infection combined with malignant tumors were diagnosed by histopathology, however, 15 patients were HIV infection alone. Results 55 cases of HIV infection combined with malignant tumors were 7-80 years old, and 46-55 years old was a high incidence of disease age, 15 patients with simple HIV infection were 35 years old （7-55 years old）. During 15 kinds of malignant tumors complicated with HIV infection,lung cancer was the most [11 cases （20 %）], followed by hepatocellular carcinoma in 5 cases （9 %）, gastric cancer in 5 cases （9 %）, and non-Hodgkin lymphoma in 5 cases （9 %）. In 70 patients with HIV infection,farmers accounted for 43 % （30 cases）, they were significantly higher than other occupations. Conclusions The age of HIV infected patients with malignant tumors is higher than that of patients with single HIV infection, which may because of immunocompromised patients have higher incidence of secondary opportunistic infections or malignant tumors. This study shows that with the extension of the survival of patients with the HIV infection, the incidence of malignant tumor is increasing.

关 键 词：HIV感染 恶性肿瘤 调查 

分 类 号：R512.91[医药卫生—内科学]