儿童血细胞异常4590例疾病构成分析  

Disease constitution analysis of 4 590 children with abnormalities in the blood cells

作　　者：常杏红[1] 郝国平[2] 冯有才[1] 

机构地区：[1]山西省儿童医院山西省妇幼保健院临检中心,太原030013 [2]山西省儿童医院血液科,太原030013

出　　处：《白血病．淋巴瘤》2015年第12期743-745,共3页Journal of Leukemia & Lymphoma

摘　　要：目的探讨骨髓细胞形态学分析在儿童血液疾病临床诊断中的意义。方法选择山西省儿童医院2009年1月至2014年12月初次骨髓穿刺检查的患儿标本4590例，对其骨髓细胞形态学分析结果进行回顾性分析。结果4590例患儿骨髓标本中婴儿期比例最高，占29．0％（1333／4590），其次为幼儿期（26．7％，1224／4590）。各年龄段均以特发性血小板减少性紫癜构成比最高。骨髓细胞形态学诊断中最常见的疾病依次为特发性血小板减少性紫癜、缺铁性贫血、感染性骨髓象、白血病（急性淋巴细胞白血病、急性髓系白血病）、再生障碍性贫血等。结论准确的骨髓细胞形态学诊断仍然是儿童造血系统疾病最基本、快捷的诊断方法，具有重要价值。除血液系统疾病外，有其他不明原因发热、肝脾大及淋巴结肿大时，也应尽早行骨髓细胞形态学检查，早期诊断，早期治疗。Objective To investigate the significance of bone marrow cell morphology on clinical diagnosis of children hematopoietic diseases. Methods The data of bone marrow cell morphology in the bone marrow puncture specimens from 4 590 children admitted to Children＇s Hospital of Shanxi Province from January 2009 to December 2014 were retrospectively analyzed. Results The proportion of infancy patients was the highest in 4 590 bone marrow specimens, accounting for 29.0 % （1 333/4 590）, then that of the toddler age patients was second highest, accounting for 26.7 % （1 224/4 590）. The constituent ratio of thrombocytopenic purpura （ITP） at the different ages was the highest. The most common diseases in bone marrow cell morphology diagnosis were in order of ITP, iron deficiency anemia （IDA）, infectious bone marrow, leukemia （acute lymphoblastic leukemia, acute myeloid leukemia）, aplastic anemia and so on. Conclusions Accurate analysis of bone marrow cell morphology is still the most basic and rapid approach in children with hematopoietic system disease, which has important value. Except bematopoietic system diseases, once fever of unknown origin, hepatosplenomegaly and enlargement of lymph nodes the patients should be early given bone marrow cell morphology check, early diagnosis and therapy.

关 键 词：儿童 骨髓细胞形态 诊断 

分 类 号：R725.5[医药卫生—儿科]