血N末端B型钠尿肽原与白细胞介素-6水平在糖尿病肾病中的关系分析  

Relationship analysis of blood N terminal B sodium urine peptide and IL-6 levels in diabetes nephrosis

作　　者：张展青[1] 何立贺 何楷燕 

机构地区：[1]揭阳市人民医院检验科,广东揭阳522000

出　　处：《华夏医学》2015年第6期61-63,共3页Acta Medicinae Sinica

摘　　要：目的:探讨糖尿病肾病患者血N末端B型钠尿肽原(NT-BNP)与白细胞介素-6(IL-6)的水平。方法:选取145例糖尿病患者为研究对象,检测患者胱抑素C(Cys C)水平作为糖尿病患者早期肾脏损伤标志,将糖尿病患者分为糖尿病肾病组(53例)和非糖尿病肾病组(92例),分别检测两组患者NT-BNP和IL-6水平。结果:糖尿病肾病组患者NT-BNP、IL-6水平高于非糖尿病肾病组患者[(4652.8±354.8)ng/L比(1123.5±121.1)ng/L,(208.7±20.5)ng/L比(82.1±11.2)ng/L],两组比较P<0.05。结论:糖尿病肾病患者血清NT-BNP、IL-6水平明显升高,可作为临床诊断糖尿病肾病的重要检测指标。Objective：To explore the relationship of blood N terminal B sodium urine peptide（NTBNP）and IL-6levels in diabetes nephrosis.Methods：145patients were served as research subjects.The level of patient bladder chalone C（Cys C）was used to take the diabetic early kidney damage indicator,and divided patients into diabetes nephrosis group（53cases）and non-diabetes nephrosis group（92cases）.The levels of NT-BNP and IL-6in the two groups were detected.Results：Serum levels of NT-BNP and IL-6in diabetes nephrosis group were obviously higher than those in non-diabetes nephrosis group（4652.8±354.8）ng/L vs（1123.5±121.1）ng/L,（208.7±20.5）ng/L vs（82.1±11.2）ng/L（P〈0.05）.Conclusion：Serum NT-BNP and IL-6levels of diabetes nephrosis patient are obvious higher,it may be used as an important detect indicator for clinical diagnosis of diabetes nephrosis.

关 键 词：N末端B型钠尿肽原 白细胞介素-6 糖尿病肾病 

分 类 号：R587.2[医药卫生—内分泌]