基于新铜试剂的Cu^2＋荧光探针的合成及性能研究  

Synthesis and Properties Study of a Neocuproine Based Fluorescent Sensor for Cu^(2+)

作　　者：常昂 吴尚荣[1,2] 柳影[2] 张鑫[2] 魏涌标[2] 李松青[1] 刘祥军[2] 上官棣华[2] 

机构地区：[1]湘潭大学化学学院,湖南湘潭411100 [2]北京分子科学国家实验室,中国科学院化学研究所活体分析化学重点实验室,北京100190

出　　处：《分析科学学报》2016年第1期58-62,共5页Journal of Analytical Science

基　　金：国家“973”计划(No.2011CB935800);国家自然科学基金(No.21275149,21375135,21321003)

摘　　要：基于新铜试剂2,9-二甲基-邻菲罗啉(NCP)对Cu2+的高选择性,本研究以NCP为母体,设计合成了Cu2+荧光探针2,9-二苯并噻唑-邻菲罗啉(PDBT)。该探针对Cu2+具有良好的选择性,Job’s plot研究表明PDBT与Cu2+的结合比为1∶1,与NCP相比,其荧光量子产率提高了7倍,对Cu2+具有高的检测灵敏度,检测限低至0.079μmol/L。进而对市售饮用水进行添加实验,得到了良好的回收率。A new fluorescent probe for copper ion,2,9-bis-benzothiazole-phenanthroline（PDBT）,was designed and synthesized based on 2,9-dimethyl-phenanthroline（NCP）.Compared with NCP,the fluorescence quantum yield of PDBT increased about 7times.PDBT showed good selectivity to copper ion over other metal ions,and high sensitivity with a low detection limit of 7.9×10-8 mol/L.Copper ion was found to bind PDBT with a stoichiometry of 1∶1.Good recoveries were obtained when the probe used in the determination of copper ion spiked in commercial drinking water.

关 键 词：新铜试剂 邻菲罗啉 荧光探针 铜离子 

分 类 号：O657.3[理学—分析化学]