不同氨气浓度饲养环境对大小鼠繁育生长性能的影响研究  

The effects of ammonia concentration on the breeding of mice and rats

作　　者：徐磊[1] 高杰[1] 张道华[1] 王胜[1] 唐涛[2] 潘永全[1] 杨根岭[1] 

机构地区：[1]重庆医科大学实验动物中心,重庆400016 [2]重庆市疾病预防控制中心

出　　处：《医学动物防制》2016年第2期183-186,共4页Journal of Medical Pest Control

基　　金：重庆市科委一般应用开发项目(cstc2014yykf A110033);动物中心内部科研项目(CQMU.LAC2015001)

摘　　要：目的研究不同氨气浓度对大小鼠繁育性能的影响。方法将性成熟的KM小鼠与SD大鼠各30对,分别饲养在氨气平均浓度为3~10 ppm（低浓度）、10~15 ppm（中浓度）、17~25 ppm（高浓度）的独立通风笼盒（Individually Ventilated Cages,IVC）内按雌雄1∶1进行交配,观察大小鼠的受孕率、产仔量、初生重、离乳率、胎次间隔与仔鼠生长情况。结果各氨气浓度组的大小鼠都能成功受孕。与中低浓度氨气组相比,高氨气浓度组KM小鼠的平均产仔量（F=3.39,P〈0.05）、初生重（F=5.40,P〈0.05）、离乳率（F=24.47,P〈0.05）、胎次间隔（F=19.32,P〈0.05）、体重增长（F=5.17,P〈0.05）、料重比（F=1.99,P〈0.05）差异均有统计学意义;高氨气浓度组SD大鼠的平均产仔量（F=5.32,P〈0.05）、初生重（F=6.86,P〈0.05）、离乳率（F=24.47,P〈0.05）、胎次间隔（F=19.32,P〈0.05）、体重增长（F=28.36,P〈0.05）、料重比（F=29.28,P〈0.05）差异均有统计学意义。结论氨气的浓度影响大小鼠的产仔量、初生重、离乳率、胎次间隔及仔鼠的生长。Objective To study the effect of different ammonia concentrations on the breeding performance of mice and rats. Methods Matured KM mice and SD rats 30 pairs of each were reared in IVC,in which the average concentration of ammonia form 3 ~ 10 ppm,10 ~ 15 ppm to 15 ~ 20 ppm,then one male mate with one female,and observe the pregnancy rate,litter weight,birth weight,weaning rate,parity interval and the growth of the offspring. Results when the concentration of ammonia is higher than 15 ppm,the litter weight,birth weight,weaning rate,parity interval and growth of the pups were significantly influenced. Conclusions The concentrations of ammonia have effect in fecundity,birth weight,weaning rate,parity interval and offspring growth of rats and mice.

关 键 词：氨气浓度 产仔量 离乳率 胎次间隔 

分 类 号：Q95-331[生物学—动物学]