患者皮下脂肪厚度与丙泊酚麻醉应用剂量相关性的临床观察  

Clinical Relevance of Subcutaneous Fat Thickness With Propofol Anesthesia Dose in Patients

作　　者：赵淑芳[1] 郭莹莹[1] 黄中梅[1] 

机构地区：[1]郑州市第六人民医院麻醉科,450005

出　　处：《中国继续医学教育》2016年第3期86-87,共2页China Continuing Medical Education

摘　　要：目的探讨与分析静脉麻醉药物丙泊酚的临床应用剂量与患者皮下脂肪厚度的相关性。方法选取2014年2月~2015年2月在我院进行甲状腺切除术患者40例,根据患者皮下脂肪厚度程度分为两组：M组（20例）：女性患者11例,皮下脂肪厚度在13~22 mm;男性患者9例,皮下脂肪厚度在5~14 mm;F组（20例）：女性患者10例,皮下脂肪厚度在22~30 mm;男性患者10例,皮下脂肪厚度在14~25 mm。结果与M组患者相比,F组入室时、麻醉诱导后、气管插管后、开始手术时、手术结束时、唤醒时的心率、血压、氧饱和值及BIS值等无明显差异,静脉麻醉药丙泊酚的临床应用计量F组患者高于M组,P〈0.05,差异具有统计学意义。结论丙泊酚使用剂量与患者脂肪含量之间存在正相关性。Objective To investigate and analyze intravenous anesthetic propofol dose and patient clinical relevance of subcutaneous fat thickness. Methods From February 2014 to February 2015, 40 patients with thyroid surgery in our hospital were selected, according to the degree of subcutaneous fat thickness divided into two groups： M group（20 cases）： 11 cases of female patients, subcutaneous fat thickness 13 to 22 mm, nine cases of male patients, subcutaneous fat thickness 5 to 14 mm, F group（20 cases）： 10 cases of female patients, subcutaneous fat thickness 22 to 30 mm, 10 male patients, subcutaneous fat thickness 14 to 25 mm. Results Compared to M group, there was no significant difference in F group of patients, while burglary, after induction of anesthesia, after intubation, at the start of surgery, end of surgery, the heart rate wakeup, blood pressure, oxygen saturation value and the BIS value and other intravenous anesthetics clinical application in F group were significantly higher than M group, P〈0. 05, with statistical significance. Conclusion There is a positive correlation between the use of propofol dose in patients with fat content.

关 键 词：丙泊酚 皮下脂肪 厚度 

分 类 号：R614[医药卫生—麻醉学]