第二代高通量测序技术的原理及其在医学中的应用进展  

The Working Principle of Second-generation High-throughput Sequencing Technology and its Application in Clinical Medicine

作　　者：杜兵兵[1] 

机构地区：[1]漯河医学高等专科学校,462002

出　　处：《中国继续医学教育》2016年第3期215-216,共2页China Continuing Medical Education

摘　　要：第二代高通量测序技术近年来取得了较快发展,与第一代测序技术相比具有速度快、准确率高、成本低等优点,主要包括454测序技术、Solexa测序技术以及SOLID测序技术。高通量测序技术在医学领域的研究越来越广泛,本文介绍了几种高通量测序技术的作用原理以及它们在临床方面的应用情况。The second-generation high-throughput sequencing technology has achieved rapid development in recent years. Compared with the first generation, the second-generation sequencing technology is with the advantages of faster, higher precision, and lower cost. The main technologies include 454 sequencing technology, Solexa sequencing technology and SOLID sequencing technology. High-throughput sequencing technology is more widely used in medical areas. This is a brief overview for the working principle of the second-generation highthroughput sequencing and its application in clinical medicine

关 键 词：高通量测序技术 454测序技术 Solexa测序技术 SOLID测序技术 临床应用 

分 类 号：G642[文化科学—高等教育学]