机械通气致肺损伤机制及治疗进展  

Mechanism and treatment progress of mechanical ventilator - induced lung injury

作　　者：任俊明[1] 郭永清[2] 

机构地区：[1]山西医科大学麻醉学系,山西省太原030001 [2]山西医科大学附属人民医院麻醉科,山西省太原030012

出　　处：《中国基层医药》2016年第1期151-154,共4页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：机械通气作为一种重要治疗手段在临床工作中被广泛应用，在其使用过程中机械通气肺损伤（VILI）较高的发生率也日益受到重视。其基本机制为机械压力和高潮气量机械刺激肺细胞使得细胞内炎性因子发生变化，即由机械性肺损伤转化为生物伤。随着国内外对VILI的研究深入，一些药物治疗、ECMO、液体通气等防治措施的应用在一定程度减少了VILI的发生，现就VILI的发生机制及治疗进展作一简要综述。Mechanical ventilation as an important treatment is widely used in clinical practice,the high incidence of ventilation lung injury in the course of operating it has been increasingly concerned. The basic mechanism, mechaical stress and high tidal volume machine stimulate lung cells, makes the inflammation in the cells changes, that is, it is from mechanical lung damage to biological injury. With the international and domestic in - depth researches on VILI, the application of control measures,like some medication treatment, ECMO, liquid ventilation have reduced the incidence of VILI to a certain extent, the occurrence mechanism and progress of treatment of VILI are reviewed briefly.

关 键 词：机械通气 肺损伤 机制 治疗进展 

分 类 号：R563.8[医药卫生—呼吸系统]