优甲乐治疗围妊娠期甲状腺功能减低的临床效果分析  

Clinical Effect Analysis of Euthyrox Treating Gestational Hypothyroidism

作　　者：任兰翠 

机构地区：[1]辽宁省抚顺市妇幼保健院,辽宁抚顺113006

出　　处：《中国医药指南》2016年第5期128-129,共2页Guide of China Medicine

摘　　要：目的探讨优甲乐治疗围妊娠期甲状腺功能减低患者的临床疗效。方法选取我院2013年9月至2015年3月300例妊娠期甲状腺功能减低患者为研究对象,根据随机数字表法分为对照组和治疗组各150例,对照组不采取任何的治疗措施,治疗组给予口服优甲乐进行治疗,随访3~6个月,观察两组患者的TSH、FT_4水平以及新生儿神经智力发育情况。结果新生儿年龄在14~30个月时检测神经智力发育情况,治疗组孕妇TSH、FT_4水平恢复正常,MDI与PDI评分显著优于对照组,两组比较差异有统计学意义（P〈0.05）。结论优甲乐治疗围妊娠期甲状腺功能减低,疗效显著,值得临床推广应用。Objective To discuss the clinical effect of Euthyrox treating gestational hypothyroidism. Methods 300 cases of gestational hypothyroidism patients in our hospital from September 2013 to March 2015 were chosen for this study and divided into a control group and a treatment group with each 150 cases. The control group did not receive any treatment, and treatment group received oral euthyrox treatment; patients were followed up for 3 to 6 months. The TSH, FT4 levels and the development of neural intelligence in two groups were observed. Results The nervous intellectual development of newborns at the age of 14 to 30 months were checked. The TSH and FT4 levels in treatment group returned to normal, MDI and PDI scores were significantly better than control group, the differences between two groups were statistically significant（P〈0.05）. Conclusion The treatment of gestational hypothyroidism with Euthyrox is significantly effective and worthy of clinical application.

关 键 词：优甲乐 围妊娠期 甲状腺功能减低 

分 类 号：R581.2[医药卫生—内分泌]