预见性治疗对防止脑外伤后脑再灌注损伤的临床意义  

The clinical significance of predictive therapy method in preventing reperfusion brain injury after brain injury

作　　者：黄锦有[1] 

机构地区：[1]广东省深圳市宝安区松岗人民医院手术室,518105

出　　处：《齐齐哈尔医学院学报》2016年第1期50-51,共2页Journal of Qiqihar Medical University

摘　　要：目的分析导致脑外伤后脑再灌注损伤的因素,探讨预见性治疗对防止脑外伤后脑再灌注损伤发生的临床意义。方法回顾性对我院自2008年2月至2015年2月因脑外伤入院病程中出现脑再灌注损伤病例进行分析,按不同的治疗策略随机抽取实施预见性治疗(预见组)和实施常规性治疗(对照组)各53例。结果对照组患者出现大面积脑梗塞15例,小面积梗塞38例;预见组患者出现大面积脑梗塞3例,小面积梗塞50例,两组之间差异有显著统计学意义(P<0.01),两组患者除GOSⅡ差异无统计学意义外(P>0.05),预见组GOSⅠ级和Ⅲ级均低于常规组、而GOSⅣ级和Ⅴ级均优于常规组,差异有显著统计学意义(P<0.01)。结论对脑外伤患者早期实施预见性治疗,就能够有效的降低脑再灌注损伤的发生,或有助于减轻脑再灌注损伤的程度。Objective To analyze the factors induced reperfusion brain injury after brain injury,and explore clinical significance of predictive therapy method in preventing reperfusion brain injury after brain injury.Methods Retrospectively analyzed the data of patients who suffered from cerebral reperfusion injury induced by traumatic brain injuries,they hospitalized in our hospital from February 2004 to February 2013,and according to the different treatment strategies they were randomly divided into predictive therapy group（ predictive group） and routine treatment group（ control group）,53 cases in each group. Results 15 cases of patients in the control group suffered large area cerebral infarction,38 cases of small area cerebral infarction. There were 3 cases of large area cerebral infarction in predictive group,50 cases of small area of infarction. There was a significant difference between the two groups（ P〈 0. 01）. The differences of GOS Ⅰ,Ⅲ,Ⅳ and Ⅴbetween the two groups were statistically significant（ P〈 0. 01）,except the GOS Ⅱ. Conclusions Early implementation of predictable treatment in patients with traumatic brain injuries,can effectively reduce the occurrence of cerebral reperfusion injury,and help to reduce the degree of cerebral reperfusion injury.

关 键 词：脑外伤 再灌注损伤 预见性治疗 预后 

分 类 号：R285.5[医药卫生—中药学]