边界振动流场对单个红细胞损伤影响分析  

Analysis of Influence on Single Eythrocyte Injury Caused by Oscillating Boundary Flow Field

作　　者：云忠[1] 向闯[1] 蔡超[1] 徐军瑞[1] 

机构地区：[1]中南大学机电工程学院,长沙410083

出　　处：《生物医学工程学杂志》2016年第1期78-82,共5页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(31271057;51475477)

摘　　要：现有的外磁驱动植入式轴流血泵,由于植入环境、受驱动力不均匀等因素会产生振动。本文通过对单个红细胞进行建模,仿真分析单个红细胞在边界振动流场中的变形与受力,并与红细胞在血泵中遭受机械损伤的机制相结合,研究边界振动流场对红细胞损伤的影响。研究结果表明,在边界振动流场中红细胞的形状变化情况、受力状况和周围速度场等因素均会导致红细胞损伤。通过对上述内容的研究,本文期待可为改善血泵的溶血现象提供理论依据。The implantable axial blood pump,driven by external electromagnet,is studied recently.It oscillats when it is running because of the elastic implanted environment and driving force disequilibrium,etc.In this paper,a model of single erythrocyte in vibrated flow field was built to simulate the deformation and force of the erythrocyte.By using the mechanical injury principle of blood in blood pump,we studied the injury of a single erythrocyte resulted from oscillating boundary flow field.The research results indicated that the shape of the erythrocyte,force and velocity field nearby,which are affected by oscillating boundary flow field,all cause injury to the erythrocyte.All the researches shown in the present paper are expected to provide theoretical foundation for lightening hemolysis by the blood pump.

关 键 词：边界振动流场 红细胞 损伤 

分 类 号：R318.01[医药卫生—生物医学工程]