江苏省启东市1987-2005年出生人群的HBsAg携带状况及变化趋势分析  

HBsAg seroprevalence and the trend of the people born during 1987-2005 in Qidong city of Jiangsu province

作　　者：倪正平[1] 陈陶阳[1] 陆玲玲[1] 卫建红 王华 黄飞[1] 施平凡[1] 

机构地区：[1]江苏省启东市人民医院、启东肝癌防治研究所,江苏启东226200 [2]江苏省启东市妇幼保健所,江苏启东226200

出　　处：《国际病毒学杂志》2016年第1期47-49,共3页International Journal of Virology

摘　　要：目的 对江苏省启东市1987-2005年出生人群的HBsAg携带状况及变化趋势进行分析.方法 对启东市1987-2005年出生者采用ELISA法或胶体金法检测血清HBsAg.结果 1987-1996年出生者HBsAg携带率分别为3.71％、4.76％、3.60％、4.70％、4.03％、3.04％、2.30％、1.60％、1.34％和1.69％;2000-2005年出生者HBsAg携带率分别为0.80％、0.60％、0.41％、0.32％和0.31％.乙肝疫苗接种覆盖率逐渐增加的19年中,1987-2005年出生人群的HBsAg携带率从最高4.76％下降至2005年的0.25％,下降幅度94.8％.提前达到卫生部2005-2010年乙肝防治规划中提出的“至2010年5岁以下儿童的HBsAg携带率降至1％以下”的标准.结论 在乙肝高发区,对新生儿接种乙肝疫苗是控制HBV的经济有效的干预措施.Objective HBsAg seroprevalence and the trend were analysed in the adolescent born during 1987-2005.Methods Serum HBsAg of the individuals born in 1987-2005 was detected using ELISA kits or colloidal gold test.Results The rates of HBsAg serum positive in 1987-1996 were 3.71%、4.76% 、3.60% 、4.70% 、4.03% 、3.04% 、2.30%、1.60%、1.34% and 1.69%,respectively.The rates during 2000-2005 were 0.80% 、0.60% 、0.41% 、0.32% and 0.31%,respectively.The coverage rate of hepatitis B vaccine was increasing in the 19 years old group.The highest rate was 4.76%,but in 2005,it decreased to 0.25%.The diminishing rate was 94.8%.The standard that the positive rate of HBsAg would drop to 1% in 2010 drew up by the Ministry of Health in 2005-2010 hepatitis B prevention and control planning had been completed ahead of schedule.Conclsions In HBV highly endemic regions,neonatal vaccination against HBV is cost-effective and necessary.

关 键 词：乙型肝炎 HBSAG 变化趋势 

分 类 号：R512.62[医药卫生—内科学]