二水合5,5'-联四唑-1,1'-二羟基的纯度分析方法  

Purity Analysis Method of 5,5'-Bistetrazole-1,1'-dyhydroxy Dihydrate

作　　者：熊书玲 陈树森[1] 李丽洁[1] 金韶华[1] 束庆海[1] 童宗睿 李京霖 

机构地区：[1]北京理工大学材料学院,北京100081 [2]甘肃银光化学工业集团公司,甘肃白银730900

出　　处：《含能材料》2016年第2期209-212,共4页Chinese Journal of Energetic Materials

基　　金：青年科技创新项目(3090041310045)

摘　　要：建立了二水合5,5′-联四唑-1,1′-二羟基（BTO）纯度的高效液相色谱分析条件： 反相色谱柱（SinoChrom ODS-BP,4.6 mm×200 mm,5 μm）,检测波长213 nm,二元流动相乙腈-水30/70（V/V）,流速1.0 mL·min-1,柱温25 ℃。采用外标法对BTO标准溶液进行定量测定,BTO浓度（c）在0.12~0.60 mg·mL-1范围内与色谱峰峰高（h）呈良好的线性关系,线性方程为h=573.78c-1.18,线性相关系数为0.9998。该法的相对标准偏差为0.48%~1.00%,平均回收率为98.10%~100.64%,方法灵敏、准确,可用于BTO 产品的纯度分析。Analysis conditions of 5,5′-bistetrazole-1,1′-dyhydroxy dihydrate（BTO）by high performance liquid chromatography（HPLC）were determined as follows：UV detection wavelength 213 nm, reversed phase column（SinoChrom ODS-BP, 4.6 mm×200 mm, 5 μm） , binary mobile phase acetonitrile and water（volume ratio of 30/70） with flow rate of 1.0 mL·min-1 at column temperature of 25 ℃. External standard method was used to analyze BTO standard solution. Results show that there is a good linearity between peak height（h）and concentration（c）from 0.12 mg·mL-1 to 0.60 mg·mL-1.The linear equation is h=573.78c-1.18 with linear correlation coefficient of 0.9998. The relative standard deviation is 0.48%-1.00% and the average recovery is 98.10%-100.64%, indicating that the method is accurate and sensitive and can be applied in the determination of BTO purity.

关 键 词：高效液相色谱 纯度分析 外标法 二水合5 5′-联四唑-1 1′-二羟基(BTO) 

分 类 号：TQ560.1[化学工程—炸药化工]