ABO血型与颈动脉粥样硬化的相关性研究  

作　　者：胡根生[1] 刘骏[1] 胡小莲[1] 徐颖[1] 谢伟[1] 

机构地区：[1]安徽省芜湖市第一人民医院心内科,241000

出　　处：《浙江临床医学》2016年第3期453-455,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨ABO血型与颈动脉粥样硬化的相关性。方法选择2014年1月至2015年1月行颈动脉超声检查的住院患者430例，按颈动脉超声检查结果分为颈动脉粥样硬化组258例（观察组）和颈动脉无粥样硬化组172例（对照组），按血型分为0型组（156例）和非。型组（274例），A型组（140例）和非A型组（290例），分析ABO血型与颈动脉粥样硬化的关系。结果A型组颈动脉粥样硬化检出率明显高于非A型组（P〈0．05）；A型组总胆固醇（TC）水平和低密度脂蛋白胆固醇（LDL-C）水平明显高于非A型组（P〈0．05）；多因素logisticS／归分析显示，校正传统危险因素：吸烟、年龄、糖尿病、高血压后，A型血[OR=1．83，95％CI1．83（1．31~3．45），P〈0．05）]是颈动脉粥样硬化的独立危险因素。结论ABO血型与颈动脉粥样硬化发生密切相关，非O血型容易罹患动脉硬化，尤其A血型发生动脉硬化风险更高。Objective To investigate the relationships between the ABO blood types and carotid atherosclerosis. Methods From January 2014 to January 2015 in the Department of Cardiology, 430 patients with carotid ultrasound from the first People＇s Hospital of Wuhu City Hospital were recruited in this study, they were divided into the carotid atherosclerosis group （ 258 cases ） and neck No artery atherosclerosis group （ control group, 172 cases ） , also they were divided into O-type group （ 156 cases ） and non-O-group （ 274 cases ） , A-type group （ 140 cases ） and non-A type group （ 290 cases ） , according to their blood type, the relationship between ABO blood group and carotid atherosclerosis were analyzed. Results The carotid atherosclerosis detection rate of was significantly higher in A blood type group than non-A type group （ P〈0.05 ） ; in A blood type group, the total cholesterol （ TC ） levels and low-density lipoprotein cholesterol （ LDL-C ） levels were significantly higher than none-A-blood type group （ P〈0.05 ） ; Multivariate logistic regression analysis showed that the correction of traditional risk factors： smoking, age, diabetes, high blood pressure later, A blood type （ OR=1.83, 95% C11.83 （ 1.31~3.45 ） , P〈0.05 ） were carotid atherosclerosis independent risk factors. Conclusion ABO blood type group and carotid atherosclerosis are closely related, the non-O blood type people is easier to suffer from arteriosclerosis, particularly blood type A people have a higher risk of arteriosclerosis.

关 键 词：ABO血型 颈动脉粥样硬化 胆固醇 

分 类 号：R543.4[医药卫生—心血管疾病]