脂炎消煎剂联合熊去氧胆酸治疗脂肪肝的临床研究  

Clinical Research on the Therapeutical Effect of Zhiyanxiao Decoction Combined with UDCA in Treatment of Fatty Liver

作　　者：程井军[1] 任婕[1] 吴其恺[2] 李凌[3] 

机构地区：[1]湖北中医药大学,湖北武汉430061 [2]广东省深圳市第三人民医院中西医结合肝病科,广东深圳508020 [3]浙江省宁波市第二医院消化专科,浙江宁波315010

出　　处：《湖北中医药大学学报》2016年第1期70-72,共3页Journal of Hubei University of Chinese Medicine

基　　金：2010年度湖北省教育厅高等学校青年教师深入企业行动计划项目(项目编号:XD2010305)

摘　　要：目的观察脂炎消联合熊去氧胆酸对脂肪肝的临床疗效。方法选择脂肪肝患者100例,随机分为治疗组50例和对照组50例,治疗组口服脂炎消煎剂联合熊去氧胆酸胶囊,对照组服用熊去氧胆酸胶囊,观察两组治疗后的总有效率、肝功能及血脂的变化。结果治疗组总有效率优于对照组(P<0.05)。治疗组丙氨酸氨基转移酶(ALT)、天门冬酸氨基转移酶(AST)和谷氨酰转肽酶(GGT)均明显降低,且优于对照组(P<0.05或P<0.01);同时总胆固醇(TC)、甘油三酯(TG)及低密度脂蛋白(LDL-c)较治疗前显著降低(P<0.05或P<0.01),其中TG与对照组比较差异有显著性意义(P<0.05),HDL-c较治疗前明显升高(P<0.05)。结论脂炎消联合熊去氧胆酸治疗脂肪肝疗效显著,能明显改善肝功能,降低血脂。Objective To observate the clinical effects of the Zhiyanxiao decoction combined with Ursodeoxy cholic Acid（ UDCA） Capsules in treatment of fatty liver. Methods 100 cases of fatty liver were randomly divided into 2 groups,the treatment group（ 50 cases） were treated with Zhiyanxiao decoction combined with UDCA Capsules,the control group（ 50 cases） were treated with UDCA Capsules. After treatment,the total efficiency rate,the markers of liver function and the levels of blood lipid were detected. Results The total efficiency rate of the treatment group was higher than that of the control group（ P〈0. 05）. ALT,AST and GGT were significantly lowered than those of the control group（ P〈0. 05 or P〈0. 01）. The level of TCh,TG and LDL- c were lowered markedly after treatment（ P〈0. 05 or P〈0. 01）.There were significant differences on TCh and TG between the two groups（ P〈0. 05）. Conclusion The curative effect of Zhiyanxiao decoction combined with UDCA is markedly effective on fatty liver. It can regulate liver function and decrease blood lipid obviously.

关 键 词：脂肪肝 中西医结合疗法 脂炎消 熊去氧胆酸 

分 类 号：R259[医药卫生—中西医结合]