超声斑点追踪技术评价尿毒症患者左室心肌分层应变  

Left Ventricular Layered Myocardial Strain in Uremia Patients Using Speckle Tracking Echocardiography

作　　者：黄冬梅[1] 崔洪岩[1] 夏稻子[1] 张宇虹[1] 礼广森[1] 

机构地区：[1]大连医科大学附属第二医院超声科,辽宁省大连市116027

出　　处：《中国超声医学杂志》2016年第2期143-146,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨超声斑点追踪技术(STI)测定左室心内膜下、中层和心外膜下心肌收缩期纵向峰值应变(SSL)评价不同构型尿毒症患者左室收缩功能的价值。方法选取65例尿毒症患者,按照左室不同构型分为左室构型正常组(LVN组,35例)和左室肥厚组(LVH组,30例),40例健康志愿者(对照组)。常规心脏数据测量后,应用STI获取所有患者心尖位3个长轴切面心内膜下、中层和心外膜下心肌SSL。结果三组间患者心肌各层SSL均保持梯度特征,即心内膜下心肌>中层心肌>心外膜下心肌;与对照组比较,LVN组心内膜下心肌SSL减低有统计学意义(P<0.05),LVH组心内膜下、中层和心外膜下心肌SSL减低均有统计学意义(P<0.05)。与LVN组比较,LVH组心内膜下心肌SSL减低有统计学意义(P<0.05)。结论不同构型尿毒症患者左室心肌受累程度不同,STI可评价尿毒症患者左室心肌分层应变。Objective To investigate the value of speckle tracking imaging（STI）in evaluating the systolic function of left ventricular subendocardium,midmyocardium and subepicardium in patients with uremia of different configurations.Methods Sixty-five patients with uremia were devided according to different configurations of left ventricule including left ventricular normal group（LVN group,n=35）and left ventricular hypertrophy group（LVH group,n=30）.Forty healthy volunteers were selected as controls.High frame rate two-dimensional images were recorded from the apical four-chamber view,two-chamber view and long-axis of the left ventricle during three consecutive cardiac cycles.Peak systolic longitudinal strain（SSL）was measured in subendocardium,midmyocardium,subepicardium.Results SSL of subendocardium was higher than that of midmyocardium,and midmyocardium was higher than that of subepicardium in three groups.Compared with the control group,SSL of subendocardium in LVN group and LVH group were significantly lower（P〈0.05）.There were significant difference in SSL of midmyocardium and subepicardium in both LVH group and control group（P〈0.05）.Compared with LVN group,SSL of subendocardium decreased in LVH group（P〈0.05）.Conclusions STI technique can sensitively reflect the change of left ventricular systolic function in patients with uremia,and provide a reference for clinical treatment.

关 键 词：超声心动描记术 尿毒症 斑点追踪 

分 类 号：R445.1[医药卫生—影像医学与核医学] R692.5[医药卫生—诊断学]