237例临床期糖尿病肾病患者中医证候聚类分析  

Cluster Analysis of Syndrome Differentiation Types of 237 Cases of Diabetic Kidney Disease in Clinical Stage

作　　者：牟新[1] 庄爱文[2] 马国玲[1] 刘颖慧[1] 胡永宾[1] 寿成珉[1] 陈家炜[1] 周旦阳[1] 

机构地区：[1]杭州市红十字会医院,浙江杭州310003 [2]浙江省中医药研究院,浙江杭州310003

出　　处：《中华中医药学刊》2016年第2期332-335,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(30801467;81273623);中国博士后基金项目(2014M551775);浙江省科技厅项目(2013C33212)

摘　　要：目的:探索临床期糖尿病肾病中医证候分布规律和方法,为进一步研究该病的病因病机及证候特点提供依据。方法:采用糖尿病肾病中医证候问卷进行横断面调查,对237例临床期糖尿病肾病患者进行调查,对所得数据进行频数统计和聚类分析。结果:糖尿病肾病患者按照出现频率排在前10位的症状总体以阴虚内热为主,进一步对症状条目进行聚类分析,得到临床期糖尿病肾病的5个证候类型。结论:糖尿病肾病为本虚标实之证,以阳虚更为明显,逐渐发展为阴阳两虚,瘀血证贯穿病程始终。Objective： To explore the distribution regularity and methodology of syndrome differentiation types of diabetic kidney disease in clinical stage based on symptoms and to provide evidences of etiology,pathogenesis and syndrome characters. Methods： We launched an investigation on 237 patients with diabetic kidney disease in clinical stage and made a frequency and cluster analysis. Results： According to frequency of occurrence of the top 10 symptoms were mainly yin deficiency. After having a cluster analysis,5 syndromes were summarized from diabetic kidney disease in clinical stage.Conclusion： Among all syndromes,root deficiency and branch excess is the basid sydnrome of diabetic kidney disease in clinical stage and Yang deficiency sydnrome is more obvious,gradually developing into Yin and Yang deficiency and blood stasis sydnrome throughout the course of the disease.

关 键 词：糖尿病肾病 聚类分析 四诊信息 中医证候 

分 类 号：R587.2[医药卫生—内分泌]