2型糖尿病患者骨质疏松骨折影响因素分析  

Influencing factors of osteoporosis and fractures in patients with type 2 diabetes mellitus

作　　者：景春贝 汪艳芳[1] 袁倩[1] 赵志刚[1] 

机构地区：[1]河南省人民医院内分泌科,郑州450003

出　　处：《中华老年医学杂志》2016年第2期217-220,共4页Chinese Journal of Geriatrics

基　　金：河南省科技厅攻关项目（132102310466）

摘　　要：2型糖尿病是一种伴有多器官受损的慢性代谢性疾病，同样累及骨骼系统，骨质疏松是2型糖尿病最易罹患的骨骼病变。研究发现，2型糖尿病患者有着更高的骨质疏松及骨折发生率，原因主要归咎于骨质量的下降和跌倒风险的增加。2型糖尿病患者骨质量下降，是骨微结构异常、骨量流失的共同结果，是2型糖尿病患者骨质疏松、骨折发生的重要原因。此外，老年2型糖尿病患者，认知和肌力下降以及步态的异常造成平衡能力下降及跌倒风险增加，从而增加骨折率。Type 2 diabetes mellitus is a kind of chronic metabolic disease, accompanied by multiple organ damages and involving the skeletal system as well. Osteoporosis is the most likely bone lesions suffered by patients with type 2 diabetes. The study found that, type 2 diabetic patients, compared with the normal people, will suffer from fracture at high risk, due to the decreased of bone quality and the increased risk of falling. The decrease of bone quality are the result of the deterioration of bone architecture and the loss of bone mass . The abnormal gait as well as the impairment of cognitive and the muscle weakness of type 2 diabetes, especially for elderly patients, will reduce their balance ability and increase their risk of falling, lead to an increased prevalence of fractures.

关 键 词：糖尿病 2型 骨质疏松 骨折 

分 类 号：R587.1[医药卫生—内分泌] R580[医药卫生—内科学]