Brugada综合征若干临床进展  

Clinical Advances on Brugada Syndrome

作　　者：胡康新[1] 潘洁[1] 姚文亮[1] 

机构地区：[1]南昌市医学科学研究所,江西南昌330001

出　　处：《心血管病学进展》2016年第1期94-97,共4页Advances in Cardiovascular Diseases

摘　　要：Brugada综合征是一遗传性致心律失常疾病，显示右心前导联（V1～V2）ST段抬高与T波倒置，而心脏结构正常。易发生心室颤动和心脏性猝死。晕厥、夜间濒死性呼吸和心脏停搏是其常见症状。近年来，Bmgada综合征的研究取得了一些进展：如揭示隐匿性Bmgada1型心电图的方法，除了药物实验外，还发现将右心前导联放置在第2肋间；用24小时动态心电图监测；早期复极（J波）对Brugada综合征预后判断有很大价值。以前，射频导管消融只针对右室流出道的外膜，现在右室流出道内膜也可做射频导管消融。Brugada syndrome is an inherited arrhythmogenic disorder that exhibits electrocadiographic ST-segment elevation with a negative T-wave in the fight preeordial leads（ V1 -V2 ） with normal heart structure, predisposing to ventrieular fibrillation and sudden cardi- ac death. Its symptoms include syncope, nocturnal agonal respiration and cardiac arrest. Recently research on Brugada syndrome has a- chieved several advances, such as early repolarization （J wave） to aid prognosis of Brugada syndrome and the change from radiofrequency catheter ablation only applied in the epicardium of right ventricular outflow tract in the past to application in the endocardium of right ventric- ular outflow tract today. Therefore the endocardium of fight ventricular outflow tract can be considered as an alternative site in the treatment of recurrent ventricular fibrillation in Brugada syndrome. Regarding exposing concealed Brugada 1 type electrogram, besides pharmacological provocation, there are two other methods： putting right precordial leads on the second intercostal space or I-lolter monitoring.

关 键 词：BRUGADA综合征 早期复极 J波综合征 射频导管消融 

分 类 号：R541.7[医药卫生—心血管疾病]