用乙酸甲酯替代丙二酸二甲酯合成二氢茉莉酮酸甲酯新工艺  

Synthesis Process of Dihydro Jasmono Acid Methyl Ester to Relace Malonic Acid with Methyl Acetate

作　　者：黄珍丽[1] 李广学[1] 房永亮[1] 施建林[1] 林伟[1] 王安顺[1] 

机构地区：[1]安徽理工大学化学工程学院,安徽淮南232001

出　　处：《安徽化工》2016年第1期38-40,43,共4页Anhui Chemical Industry

基　　金：大学生创新创业训练计划项目(201510361230)

摘　　要：以环戊酮和正戊醛为原料,经缩合和异构化反应合成2-戊基环戊烯酮,再与乙酸甲酯在碱性试剂作用下进行Michael加成,合成二氢茉莉酮酸甲酯。产物经过核磁共振氢谱、红外等方法进行表征和定性、定量测定,结果表明,所合成产物是二氢茉莉酮酸甲酯。在所选择的合理的反应条件下,产率为42%。With cyclopentanone and valeraldehyde as raw material, by condensation and isomerization reaction of synthesis of 2- pentyl cyelopentenone, again with methyl acetate under the effect of alkaline reagents for Michael addition, synthetic methyl dihydrojasmonate. Products through the 1HNMR, IR and other methods of characterization and qualitative, quantitative determination, the results show that the synthesized product is methyl dihydrojasmonate, at select proper reaction conditions , the production rate of 42%.

关 键 词：二氢茉莉酮酸甲酯 环戊酮 正戊醛 乙酸甲酯 

分 类 号：TQ655[化学工程—精细化工]