四维自动左室定量技术评价系统性红斑狼疮患者左室收缩功能的初步研究  被引量:2

Evaluation of left ventricular systolic function in patients with systemic lupus erythematosus using four dimensional automatic left ventricular quantify:a preliminary study

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作  者:钱胜利[1] 杨莉[1] 高菡静[1] 李延[1] 张俊[1] 乔伟[1] 

机构地区:[1]中国人民解放军第161医院特诊科,湖北武汉430010

出  处:《中国临床医学影像杂志》2016年第2期106-109,共4页Journal of China Clinic Medical Imaging

摘  要:目的:探讨四维自动左室定量技术(Four dimensional automatic left ventricular quantify,4D Auto LVQ)早期评价系统性红斑狼疮(SLE)患者左室收缩功能的临床应用价值。方法:收集SLE患者28例及正常对照组30例,分别应用4D Auto LVQ技术获得左室舒张末期容积(EDV)、收缩末期容积(ESV)、左室射血分数(LVEF)、心输出量(CO)、球形指数(SPI)、左室舒张末期质量(LV EDmass)及质量指数(LV EDmassⅠ)、左室收缩末期质量(LV ESmass)及质量指数(LV ESmassⅠ);左室整体纵向应变(GLS)及局部纵向应变(LS)、整体圆周应变(GCS)及局部圆周应变(CS)、整体面积应变(GAS)及局部面积应变(AS)、整体径向应变(GRS)及局部径向应变(RS),比较两组参数之间的差异。结果:与对照组比较,SLE组虽然LVEF降低、SPI增高,但差异无统计学意义(P>0.05)。SLE组EDV、ESV、CO、LV EDmass、LV ESmass&LV EDmassⅠ、LV ESmassⅠ均较对照组明显增高(P<0.05),两组受试者整体心肌应变(GLS、GCS、GAS、GRS)及大部分节段心肌应变(LS、CS、AS、RS)比较:SLE组均较对照组显著减低(P<0.05)。结论:4D Auto LVQ技术可早期评价SLE患者左室整体及局部心肌收缩功能受损情况。Objective: To explore the value of four dimensional automatic left ventricular quantify(4D Auto LVQ) to assess left ventricular systolic function early in patients with systemic lupus erythematosus(SLE). Methods: Twenty-eight SLE patients and thirty control subjects underwent the examination of 4D Auto LVQ obtain the segments of left ventricular end-diastolic volume(EDV), left ventricular end-systolic volume(ESV), left ventricular ejection fraction(LVEF), cardiac output(CO), spherical index (SPI), left ventricular end-systolic mass (LV ESmass) and left ventricular end-systolic mass index (LV ESmass I ), left ventricular end-diastolic mass (LV EDmass) and left ventricular end-diastolic mass index (LV EDmass I ), global longitudinal strain(GLS) and longitudinal strain(LS), global circumferential strain(GCS) and circumferential strain(CS), global area strain(GAS) and area strain(AS), global radial strain(GRS) and radial strain(RS). Values of these parameters between two groups were com- pared. Results: Compared with those of the controls, though LVEF lower and SPI higher in SLE groups, but there were no statistically significant difference between the two groups (P〉0.05). EDV, ESV, CO, LV EDmass, LV ESmass and LV EDmass ( LV ESmass )were significantly higher in SLE group (P〈0.05). GLS, GCS, GAS, GRS and the most of the segments's strains were decreased in SLE patients compared with controls (P〈0.05). Conclusion: 4D Auto LVQ can be used as early evaluation of left ventricular global and local myocardial systolic function which was damaged in patients with SLE.

关 键 词:心室功能  收缩 红斑狼疮 系统性 超声心动描记术 多普勒 彩色 

分 类 号:R331.31[医药卫生—人体生理学]

 

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