热脱附-气相色谱-三重四极杆串联质谱法测定环境空气中的挥发性有机物  

Determination of volatile organic compounds in ambient air by thermal desorption-gas chromatography-triple quadrupole tandem mass spectrometry

作　　者：冯丽丽[1] 胡晓芳[1] 于晓娟[1] 张文英[1] 

机构地区：[1]上海交通大学环境科学与工程学院,上海200240

出　　处：《色谱》2016年第2期209-214,共6页Chinese Journal of Chromatography

摘　　要：采用热脱附（TD）结合气相色谱-三重四极杆串联质谱（GC-MS/MS）建立了环境空气中23种挥发性有机物（VOCs）同时检测的分析方法。空气样品通过主动采样的方式富集到装有Tenax-TA填料的热脱附管中,热解吸后在选择反应监测（SRM）模式下用GC-MS/MS进行检测,内标法定量。结果表明,23种VOCs在0.01~1 ng和1~100 ng低、高两个范围内线性关系良好,相关系数（r2）均大于0.99,方法定量限为0.000 08~1μg/m3。加标水平为2、10和50 ng时,23种VOCs的平均回收率为77%~124%。除了最低加标水平的氯苯,相对标准偏差（RSD,n=6）均小于20%。对市内3个采样点的环境空气进行测定,其中苯、甲苯、乙苯、二甲苯、苯乙烯、1,2,4-三甲基苯和六氯丁二烯均有检出。实验证明,该TD和GC-MS/MS相结合的检测方法具有准确、可靠、灵敏度高等优点,适用于环境空气中VOCs的同时测定。A method was established for the simultaneous determination of 23 volatile organic compounds（VOCs）in ambient air with combination of thermal desorption（TD）and gas chromatography-triple quadrupole tandem mass spectrometry（GC-MS / MS）. The air samples were collected by active sampling method using Tenax-TA sorbent tubes,and desorbed by thermal desorption. The analytes were determined by GC-MS / MS in selected reaction monitoring（SRM）mode,and internal standard method was applied to quantify the VOCs. The results of all the 23 VOCs showed good linearities in low level（0. 01- 1 ng）and high level（1- 100 ng）with all the correlation coefficients（r2）more than 0. 99. The method quantification limits were between 0. 000 08-1 μg / m3. The method was validated by means of recovery experiments（n =6）at three spiked levels of 2,10 and 50 ng. The recoveries between 77% and 124% were generally obtained. The relative standard deviations（RSDs）in all cases were lower than 20%,except for chlorobenzene at the low spiked level. The developed method was applied to determine VOCs in ambient air collected at three sites in Shanghai. Several compounds,like benzene,toluene,ethylbenzene,m-xylenes,p-xylenes,styrene,1,2,4-trimethylbenzene and hexachlorobutadiene were detected and confirmed in all the samples analyzed. The method is highly accurate,reliable and sensitive for monitoring the VOCs in ambient air.

关 键 词：热脱附 气相色谱-三重四极杆串联质谱 挥发性有机物 环境空气 

分 类 号：O658[理学—分析化学]