米非司酮联合甲氨蝶呤在宫外孕治疗中的临床疗效分析  

Analysis the Clinical Curative Effect of Mifepristone Combined With Methotrexate in Treatment of Ectopic Pregnancy

作　　者：金海鸿[1] 

机构地区：[1]黑龙江省医院,哈尔滨150036

出　　处：《中国继续医学教育》2016年第4期154-155,共2页China Continuing Medical Education

摘　　要：目的探讨宫外孕患者接受米非司酮和甲氨蝶呤联合治疗的效果。方法选取2012年4月～2013年12月我院的60例宫外孕患者进行探讨分析,将患者分为对照组和研究组,各30例。对照组接受甲氨蝶呤治疗,研究组接受米非司酮和甲氨蝶呤联合治疗,对两组的临床不良反应发生率进行对比分析。结果研究组临床治愈率是96.7%,无效比例3.3%,5例不良反应,发生率是16.7%。对照组的治愈率是73.3%,无效比例26.7%,14例不良反应,发生率是46.7%。研究组临床治疗效果优于对照组,对照组不良反应发生率高于研究组,结果存在统计学差异性。结论宫外孕患者使用米非司酮联合甲氨蝶呤治疗的效果好,优于单纯的甲氨蝶呤治疗。Objective To investigate the effect of combined therapy of mifepristone and methotrexate in patients with ectopic pregnancy. Methods Selected 60 cases of ectopic pregnancy from April 2012 to December 2013 in our hospital, which were divided into the control group and the study group, each group had 30 cases. the control group were treated with methotrexate, and the study group received mifepristone and methotrexate therapy. The incidence rate of adverse reactions in the two groups were compared and analyzed. Results The clinical cure rate of the study group was 96.7%, the effective rate was 3.3%, there were 5 cases of adverse reactions, the incidence rate was 16.7%. The cure rate of the control group was 73.3%, the effective ratio was 26.7%, there were 14 cases of adverse reactions, the incidence rate was 46.7%. The clinical treatment effect of the study group was better than that of the control group, the incidence rate of adverse reaction in the control group was higher than that of the study group, and the results were statistically significant. Conclusion Mifepristone combined with methotrexate treatment of ectopic pregnancy patients with good results, due to the simple methotrexate treatment, can be used to promote the treatment.

关 键 词：米非司酮 甲氨蝶呤 宫外孕 治疗 临床疗效 

分 类 号：R714.22[医药卫生—妇产科学]