中小剂量甲泼尼龙联合甲氨蝶呤与硒酵母对Graves眼病的疗效观察  

The therapeutic efficacy of middle- and low-dose methylprednisoione combined with methotrexate and selenium yeast on Graves ophthaimopathy

作　　者：张祎[1] 张险峰[1] 韩辉[1] 黄佼[1] 马丽珍[1] 张楚[1] 

机构地区：[1]南京医科大学附属杭州医院杭州市第一人民医院内分泌代谢科,310006

出　　处：《中华内分泌代谢杂志》2016年第1期24-26,共3页Chinese Journal of Endocrinology and Metabolism

基　　金：浙江省自然科学基金项目

摘　　要：观察Graves眼病（GO）患者使用中小剂量甲泼尼龙联合甲氨蝶呤的治疗效果，并评价在此基础上加用硒酵母是否可能获益。结果显示中小剂量甲泼尼龙联合甲氨蝶呤对中重度GO患者治疗有效，加用硒酵母并不能进一步改善病情。The efficacy of the combining therapy of methylprednisolone and methotrexate on the Graves ophthalmopathy （GO） was observed. Whether selenium supplement is beneficial based on this combining therapy scheme was evaluated. The results showed that the combining therapy of methylprednisolone and methotrexate was effective for the patients with moderate-to-severe GO. Selenium supplement did not further improve the remission of GO.

关 键 词：GRAVES眼病 甲基泼尼松龙 甲氨蝶呤 硒酵母 

分 类 号：R581.1[医药卫生—内分泌]