高效液相色谱-串联质谱法测定纺织品中16种全氟烷酸类化合物  

Determination of 16 Perfluoroalkyl Acids in Textiles by HPLC-MS/MS

作　　者：郑建国[1] 刘葳[2] 张子豪[1] 刘莹峰[1] 李全忠[1] 李丹[1] 彭莹[1] 张增强[2] 周明辉[1] 

机构地区：[1]广东出入境检验检疫局,广东广州510623 [2]五邑大学纺织服装学院,广东江门529020

出　　处：《分析测试学报》2016年第2期213-218,共6页Journal of Instrumental Analysis

基　　金：国家质检总局科研项目(2013IK003;2013IK095);质检公益性行业科研专项(2012104020)

摘　　要：采用高效液相色谱-串联质谱（LC-MS/MS）技术建立了纺织品中16种全氟烷酸类化合物的测定方法。样品以甲醇为溶剂,超声提取,C18（100 mm×2.1 mm,2.7μm）色谱柱分离,流动相为水和甲醇,梯度洗脱,多反应监测（MRM）模式进行分析检测。16种全氟烷酸类化合物在1~1 000 ng/m L浓度范围内与对应峰面积呈线性关系。方法定量下限（S/N=10）为0.21~1.53μg/m2。加标回收率为84.8%~107.4%,相对标准偏差（RSD）不大于7.2%。该方法快速简便、准确可靠,适用于纺织品中全氟烷酸类化合物的分析检测。A high performance liquid chromatography-tandem mass spectrometric（ HPLC-MS / MS）method was developed for the determination of 16 perfluoroalkyl acids in textiles. Samples were extracted with methanol through ultrasonic method. The target ingredients were separated on a C18column（ 100 mm × 2. 1 mm,2. 7 μm） using a mixture of methanol-water system as mobile phase by gradient elution. The 16 perfluoroalkyl acids were analyzed by MS under multiple reaction monitoring mode（ MRM）. The linear ranges of 16 perfluoroalkyl acids were between 1 ng / m L and 1 000 ng / m L.The limits of quantitation were between 0. 21 μg / m2 and 1. 53 μg / m2. The recoveries ranged from84. 8% to 107. 4%,with relative standard deviations（ RSDs,n = 6） not more than 7. 2%. This method was fast,sensitive,accurate,precise and convenient to operate,and it was appropriate for the determination of perfluoroalkyl acids in textiles in routine tests.

关 键 词：纺织品 全氟烷酸 高效液相色谱-串联质谱 测定 

分 类 号：O657.63[理学—分析化学] F768.1[理学—化学]