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作 者:王力[1] 高瑞岭[1] 吴海建[1] 张霞[1] 梁成[1] 刘斌[1] 苏心镜[1]
机构地区:[1]河北北方学院附属第二医院,河北张家口075100
出 处:《吉林中医药》2016年第2期205-207,共3页Jilin Journal of Chinese Medicine
基 金:河北省张家口市科学技术研究与发展计划项目(1421102D)
摘 要:目的探讨针刺联合窄谱中波紫外线治疗斑秃的临床疗效。方法选取2012年3月—2013年11月来本院确诊的斑秃患者60例,随机分为观察组及对照组,各30例,观察组采用针刺法联合窄谱中波紫外线治疗,对照组仅进行针刺治疗。对比2组患者治疗前后症状、体征评分、匹兹堡睡眠质量指数(PSQI)改善情况,并对比血清中血管内皮生长因子(VEGF)变化及临床疗效。结果 2组治疗后症状、体征评分及PSQI评分较治疗前明显改善(P<0.05),观察组治疗后两项评分改善幅度优于对照组(P<0.05);2组治疗后血清VEGF较治疗前显著上升(P<0.05),观察组治疗后血清VEGF水平〔(129.4±30.5)ng/L〕明显高于对照组〔(107.8±28.2)ng/L〕(P<0.05);观察组总有效率100%,显著高于对照组86.7%(P<0.05)。结论针刺联合窄谱中波紫外线可有效缓解斑秃患者临床症状,并能提高血清VEGF水平。Objective To explore the clinical efficacy of acupuncture in combined with narrow band ultraviolet in the treatment of alopecia areata. Methods A total of 60 patients confirmed with alopecia areata who were admitted in our hospital from March,2012 to November,2013 were included in the study and randomized into the observation group and the control group with 30 cases in each group. The patients in the observation group were given acupuncture in combined with narrow band ultraviolet,while the patients in the control group were only given acupuncture. The symptom and sign scores,the improvement of PSQI,the serum VEGF,and the clinical efficacy before and after treatment in the two groups were compared. Results The symptom,sign,and PSQI scores after treatment in the two groups were significantly improved when compared with before treatment 〔( 129. 4 ± 30. 5) ng / L〕( P〈0. 05),and the improved degree in the observation group was significantly superior to that in the control group〔( 107. 8 ± 28. 2) ng / L〕( P〈0. 05). The serum VEGF degree after treatment in the two groups was significantly increased when compared with before treatment( P〈0. 05),and the increased degree in the observation group was significantly superior to that in the control group( P〈0. 05). The total effective rate in the observation group 100% was significantly higher than that in the control group 86. 7%( P〈0. 05). Conclusion Acupuncture in combined with narrow band ultraviolet in the treatment of alopecia areata can effectively relieve the clinical symptoms and enhance the serum VEGF level.
关 键 词:斑秃 针灸疗法 窄谱中波紫外线 穴 百会 穴 头维 穴 风池
分 类 号:R246[医药卫生—针灸推拿学]
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