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机构地区:[1]四川大学华西第二医院新生儿科,成都610041 [2]泸州医学院附属医院新生儿科
出 处:《华西医学》2016年第2期262-265,共4页West China Medical Journal
摘 要:目的探讨新生儿呼吸衰竭(NRF)的发病、治疗及预后情况。方法对2011年1月-2013年12月四川大学华西第二医院新生儿科收治的421例NRF患儿的临床资料进行回顾性分析。结果 NRF发生率为4.8%,病死率为14.5%。原发疾病以新生儿呼吸窘迫综合征(36.1%)及吸入性肺炎(29.0%)较为常见。呼吸机辅助通气是NRF的主要治疗措施(77.2%)。早产(χ2=12.216,P<0.001)、低出生体质量(χ2=8.932,P=0.003)及出生后窒息(χ2=6.199,P=0.013)与NRF预后密切相关,系NRF病死的高危因素。结论 NRF是一种高发病率、高病死率的疾病,做好有效的防治工作对提高NRF患儿的救治成功率有重要的意义。Objective To explore the incidence, treatment and prognosis of neonatal respiratory failure(NRF). Methods The clinical data of 421 neonates with NRF treated between January 2011 and December 2013 were retrospectively analyzed. Results The incidence and the mortality of NRF was 4.8% and 14.5%, respectively. The main primary disease of NRF was neonatal respiratory distress syndrome(36.1%) and aspiration pneumonia(29.0%). Mechanical ventilation was the main treatment for NRF(77.2%). Premature(χ2=12.216, P〈0.001), low birth weight(χ2=8.932, P=0.003) and the neonatal asphyxia(χ2=6.199, P=0.013) were closely related to the prognosis of NRF, which were the risk factors of the death of NRF. Conclusion NRF is a disease with high incidence and high mortality; make effective prevention and treatment measures are important to improve the success rate of therapy for NRF.
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