基于光谱法的清脑复神液指纹图谱研究  

Study on the spectrum fingerprints of Qingnaofushen oral liquid

作　　者：刘涛[1] 伍利华[1] 黄英 李鹏程[1] 张文文[1] 徐玉玲[1] 

机构地区：[1]成都大学,四川成都610106 [2]四川新中方医药科技股份有限公司,四川广元628000

出　　处：《中国测试》2016年第2期63-66,共4页China Measurement & Test

基　　金：四川省经信委产业技术研究与开发基金项目(20141124);四川省科技厅科技支撑计划项目(2014SZ0139)

摘　　要：为建立清脑复神液的紫外及红外指纹图谱评价方法,采用紫外可见分光光度计和红外光谱仪分别测定20批清脑复神液,建立清脑复神液的对照紫外及红外指纹图谱,并采用相关系数法计算清脑复神液样品指纹图谱与对照指纹图谱的相似度。在紫外指纹图谱中,含量符合规定的样品,其紫外图谱与对照图谱的相似度均在0.995以上,而含量不符合规定的4批样品,则相似度<0.993;红外指纹图谱中,含量符合规定的样品,其红外图谱与对照图谱的相似度均在0.990以上,而含量不符合规定的4批样品,则相似度<0.980。该方法可用于脑复神液的质量评价,其相似度值的大小可作为清脑复神液质量的评价指标。To establish the evaluation methodology of Qingnaofushen oral liquid by ultraviolet and infrared fingerprints, the ultraviolet and infrared diagrams for 20 batches of Qingnaofushen oral liquid were measured through an ultraviolet visible spectrophotometer and an infrared spectrometer. Then established the ultraviolet and infrared fingerprints by using common pattern and calculated the similarity by using correlation coefficient method. The similarity between the ultraviolet fingerprints and the control fingerprints of qualified samples was above 0.995 whereas that of the four unqualified batches was below 0.993. The similarity between the infrared fingerprints and the control fingerprints of the qualified samples was higher than 0.990 while that of the four unqualified batches was lower than 0.980. It is thus demonstrated that this method can be used to evaluate the quality of Qingnaofushen oral liquid and the similarity can be regarded as an anevaluating indicator.

关 键 词：清脑复神液 质量评价 紫外指纹图谱 红外指纹图谱 

分 类 号：Q949.777.7[生物学—植物学]