基于临床表现的中药不良反应判断及防护方法  

Protective measures of ADR caused by TCM on basis of clinical manifestations

作　　者：蒋健[1] 

机构地区：[1]上海中医药大学附属曙光医院,上海200021

出　　处：《长春中医药大学学报》2016年第1期83-87,共5页Journal of Changchun University of Chinese Medicine

基　　金："十二五"重大新药创制"创新药物研究开发技术平台建设"(2012ZX09303009-001);上海市教委重点学科中药临床药理学(J50303)

摘　　要：中医临床个体化治疗及中药复方治疗的特性均为判断中药不良反应带来一定的困难。为弥补通过实验室检测和数据库检索判断药物不良反应的不足,基于具体的案例分析,强调从患者临床表现的变化中捕捉中药不良反应的可能信息并加以确证与防护,即停药观察法、减量观察法、大剂量观察法(近于减量观察法)、动物药观察法(近于停药观察法)、既往用药史观察法及"留观"观察法等判断中药不良反应的方法。The difficulties to judge the ADR caused by TCM is due to the combination of the characteristics of TCM and the individualized treatment in TCM clinic. To make up the shortages of judging ADR by laboratory tests and database retrieval,some specific cases are analyzed in this paper and 6 judgement methods and protective measures are proposed. Those measures are the drug withdrawal observation,decrement observation,incremental observation（ similar to the decrement observation）,animal medicine observation（ similar to the drug withdrawal observation）,past medical history observation and under observation to judge the ADR of TCM,which are based on capturing the information of ADR from the changes of the clinical manifestations of patients.

关 键 词：中药 不良反应 医案 

分 类 号：R248[医药卫生—中医临床基础]