血浆B型钠尿肽、肌钙蛋白对急性心肌梗死后心功能的预测价值  

Predictive Value of Plasma B-type Natriuretic Peptide,Troponin for Heart Function of Acute Myocardial Infarction

作　　者：王晓林[1] 张亚军[1] 霍建凤 邹宁[1] 王娜[1] 冯亮飞[1] 朱红新[1] 赵萍[1] 

机构地区：[1]秦皇岛市第二医院心内科,秦皇岛066600

出　　处：《中国医药导刊》2016年第2期140-141,144,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨血浆B型钠尿肽、肌钙蛋白对急性心肌梗死后心功能的预测价值。方法:选取我院收治的急性心肌梗死患者136例患者,测定BNP和CtnⅠ值,随访1年后测定患者的LVDd、LVEF%和NYHA心功能分级。分析急性发病3天后的血浆BNP和CtnⅠ值与随访1年后心功能的关联性。结果:随着患者血浆BNP含量增加,患者的LVEF%值在减小,呈负相关(P<0.05);随着患者血浆CtnⅠ含量增加,患者的LVEF%值在在增加,呈正相关(P<0.05);随着患者血浆BNP含量增加,患者的NYHA心功能分级在增加,呈正相关(P<0.05);随着患者血浆CtnⅠ含量增加,患者的NYHA心功能分级在减少,呈负相关(P<0.05)。结论:血浆B型钠尿肽、肌钙蛋白对急性心肌梗死后心功能有重要预测价值。Objective: To explore the predicted value of plasma b-type natriuretic peptide(BNP) and troponin to function after acute myocardial infarction.Methods:136 patients with acute myocardial infarction in our hospital,CtnⅠ and BNP were measured,and the LVDd,LVEF% and NYHA heart function classification were determined after 1 years of follow-up.The relationship between plasma CtnⅠ and BNP after 3 days of acute onset and cardiac function after 1 years of follow-up was analyzed.Results:With the increase of plasma BNP level, patients with LVEF% were negatively correlated(P<0.05); with the increase of CtnⅠ content,the LVEF% value was positively correlated(P<0.05); with the increase of BNP content in patients,patients with NYHA increased, and the level of NYHA in patients with CtnⅠ was decreased,and negative correlation(P<0.05) was negative.Conclusion:There have significant predictive value of BNP and troponin to the function after acute myocardial infarction.

关 键 词：B型钠尿肽 肌钙蛋白 心肌梗死 

分 类 号：R542.22[医药卫生—心血管疾病]