三通骨痛膏质量控制方法研究  

Study on Quality Standard for Santong Gutong Paste(三通骨痛膏)

作　　者：饶伟源[1] 王丽[1] 兰保强[1] 邓聿胤[1] 

机构地区：[1]广西中医药研究院,广西南宁530022

出　　处：《中医药导报》2016年第4期47-48,52,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：广西壮族自治区卫生厅中医药科技专项项目(GZZJ13-14)

摘　　要：目的：为三通骨痛膏建立质量标准。方法：采用TLC法对制剂中的飞龙掌血、没药、龙血竭和大黄进行定性鉴别,用HPLC法对丹皮酚进行含量测定。结果：TLC法可鉴别出制剂中的飞龙掌血、没药、龙血竭和大黄;定量测定丹皮酚在0.0815-0.815 g范围内呈良好线性关系,相关系数为r=0.9999,方法回收率平均值为99.17%,RSD%为0.77%。结论：本法准确、快速、简便、重复性好,可作为三通骨痛膏的主要质量控制指标。Objective： To develop a quality standard for Santong Gutong paste. Methods： Toddalia asiatica, C. myrrha, Resina Draconis and Rheum palmatum L were indentified by TLC. The content of Paeonol in the tincture was determined by HPLC. Results： Toddalia asiatica, C.myrrha, Resina Draconis and Rheum palmatum L could be distinguished by TLC. Paeonol in the range of 0.0815-0.815 g has a good linear relationship （r=0.9999）. The average recovery rate was 99.17% （RSD%=0.77%）. Conclusion： The method was accurate, quick, simple and with good reproducibility for the quality control of Santong Gutong paste.

关 键 词：三通骨痛膏 薄层色谱法 丹皮酚 高效液相色谱法 

分 类 号：R284.1[医药卫生—中药学]