消痛通络方内服外用治疗膝骨关节炎的临床观察  

Clinical Study on Treatment of Knee Osteoarthristis with Xiaotong Tongluo Decoction(消痛通络方)

作　　者：刘樱[1] 覃光辉[2] 吴宏进 尹磊淼[1] 张志枫[4] 

机构地区：[1]上海市针灸经络研究所,上海200030 [2]上海市闸北区中心医院,上海200435 [3]上海市龙华医院,上海200030 [4]上海中医药大学,上海201203

出　　处：《中医药导报》2016年第4期75-76,79,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金资助项目(81173200);上海市卫生系统优秀青年人才培养计划(XYQ2013081)

摘　　要：目的:观察消痛通络方治疗膝骨关节炎的临床疗效。方法:采用随机、平行对照研究方法,将中医辨证为肝肾两虚合并瘀血痹阻证膝骨关节炎患者40例分为治疗组、对照组,治疗4周。观察记录各组治疗前后临床症状、膝关节功能活动及不良反应情况,进行统计分析比较。结果:经临床治疗4周后,两组患者膝关节晨僵时间、关节压痛、肿胀、疼痛与治疗前比较,均有明显改善(P<0.05);治疗组和对照组疗效相当,差异无统计学意义(P>0.05)。结论:消痛通络方治疗膝骨关节炎临床效果良好,无明显不良反应。Objective： To observe the clinical effects of Xiaotong Tongluo Decoction （XTYLD, 消痛通络方） on knee osteoarthritis. Methods： The 40 patients with knee osteoarthritis, whose type were deficiency of the both the liver and kidney combined with blood stasis, were divided into treatment group and control group randomly, treating for 4 weeks. Each clinical symptom before and after the treatment, and adverse reaction of knee joint function activities were observed. Results： After the treatment, the time of morning stiffness, joint tenderness, swelling, pain of the two groups improved significantly （P〈0.05）. While the clinical effects of the two groups showed no statistical significance （P〉0.05）. Conclusions： XTI＇LD has good effects on knee osteoarthritis, and has no obvious adverse reactions.

关 键 词：膝骨关节炎 消痛通络方 肝肾两虚 瘀血痹阻 

分 类 号：R255.6[医药卫生—中医内科学]