热敏灸治疗周围性面瘫随机/半随机对照试验的Meta分析  

Meta Analysis on Clinical Randomized/Semi-randomized Controlled Trials of Heat-sensitive Moxibustion for Peripheral Facial Paralysis

作　　者：梁丽嫦[1] 莫秋红[1] 廖建琼[1] 王明春[1] 王升旭[1] 

机构地区：[1]南方医科大学,广东广州510515

出　　处：《中医药导报》2016年第4期110-114,共5页Guiding Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:系统评价热敏灸治疗周围性面瘫的临床疗效,为临床治疗及开展相关研究提供参考和帮助。方法:计算机检索Pub Med、Springer、中国生物医学文献数据库(CBMdisc)、中国知网(CNKI)、维普数据库(VIP)、万方数据库,文献检索起止时间均从建库到2015年1月,纳入热敏灸治疗周围性面瘫的临床随机/半随机对照试验文献,试验数据用Revman5.2软件进行Meta分析。结果:共检索到随机/半随机对照试验12个,1039例患者纳入本次研究。12个试验均以有效率作为结局指标,显示热敏灸组与对照组比较,合并后RD=0.07,95%CI[0.03,0.10]。总体效应检验,Z=3.76,P<0.01,两组在治疗周围性面瘫方面疗效比较,差异有统计学意义(P<0.01)。亚组分析:热敏灸组VS常规针刺组,合并后RD=0.06,95%CI[0.02,0.10]。总体效应检验,Z=2.78,P<0.01,两组在治疗周围性面瘫方面疗效比较,差异有统计学意义(P<0.01)。结论:热敏灸组治疗周围性面瘫临床疗效优于对照组。同时,热敏灸具有无痛苦、患者接受度高、操作简单的优势,建议临床医生根据实际情况选择热敏灸综合治疗周围性面瘫。可靠结论尚需大样本、多中心、设计良好的随机对照试验来进一步验证。Objective： To systemically analyze the clinical therapeutic effect of heat-sensitive moxibustion on peripheral facial paralysis, and to provide reference and assistance for its clinical treatment and research. Methods： Conducting literature retrieval through the PubMed, Springer, China Biology -Medicine disc （CBMdisc）, China Hownet（CNKI）, Vip database （VIP） and Wanfang databases, and all the collected literature should be published between the establishing time of databases and January 2015; Integrating literature about the clinical randomized/semi-randomized controlled trials of heat-sensitive moxibustion for peripheral facial paralysis and applying Revman 5.2 for the meta-analysis of experimental data. Results： Totally 12 randomized/semi- randomized controlled trials were acquired with 1039 cases involved in the study. The effective rate was selected as primary outcome measure in the 12 trials. The Meta-analysis was performed among homogeneous researches. The results indicated that heat-sensitive moxibustion group compared with the control group,pooled RD of heat-sensitive moxibustion group was 0.07 with 95% CI [0.03, 0.10]. In the test for overall effect, implying the efficacy difference of two groups was significant in the treatment of peripheral facial paralysis （Z= 3.76, P〈0.01）. In subgroups analysis, heat-sensitive moxibustion group compared with the conventional acupuncture group,pooled RD of heat-sensitive moxibustion group was 0.06 with 95% CI [0.02, 0.10]. In the test for overall effect, implying the efficacy difference of two groups was significant in the treatment of peripheral facial paralysis （Z=2.78, P〈0.01）. Conclusions： The clinical efficacy of heat-sensitive moxibustion group is superior to the control group of peripheral facial paralysis. Meanwhile, the heat-sensitive moxibustion has some advantages： no pain, patients receiving high, simple operation. It is suggested that clinical doctors should choose cupoints ihermal moxibustion combined with other treatmen

关 键 词：热敏灸 周围性面瘫 META分析 

分 类 号：R246[医药卫生—针灸推拿学]