肺炎支原体肺炎患儿血清炎性因子的变化及其意义探讨  

Changes in the Peripheral Blood of Children with Mycoplasma Pneumonia and Discussion on the Significance of Inflammatory Cytokines

作　　者：朱勇斌[1] 徐海玲[1] 林耿亮 

机构地区：[1]广东省揭阳市人民医院,广东揭阳522000

出　　处：《中国医学创新》2016年第4期27-29,共3页Medical Innovation of China

摘　　要：目的:通过观察肺炎支原体肺炎(MPP)患儿血清炎性因子的变化,探讨其在肺炎支原体肺炎临床诊治中的意义。方法:选取本院2014年1月-2015年4月接诊的支原体肺炎患儿30例作为观察组,另选取30例正常儿童作为对照组,分别采用全自动生化分析仪测定60例儿童血清C-反应蛋白(CRP)、应用免疫荧光法检测降钙素原(PCT)及运用生化比色法测定特异性生长因子(TSGF)水平,比较两组儿童血清炎性因子含量情况。结果:观察组患儿血清中CRP、PCT及TSGF三种炎性因子的含量均明显高于对照组,比较差异有统计学意义(P<0.05)。结论:患儿血清CRP、PCT和TSGF炎性因子含量增高可为MPP的诊治提供重要的参考依据,具有较广泛的临床意义。Objective： To observe and explore the changes in children with mycoplasma pneumonia inflammatory cytokines in peripheral blood and its significance in the clinical diagnosis and treatment of mycoplasma pneumonia.Method： 30 children with mycoplasma pneumonia in our hospital from January 2014 to April 2015 were selected as research group, and another 30 normal children were selected the control group.The automatic biochemical analyzer was applied to measure the serum C-reactive protein （ CRP ）, the immunofluorescence was applied to measure the procalcitonin （ PCT ）, and the biochemical colorimetric determination was applied to measure the tumor specific growth factor （ TSGF ） .Result： The content of CRP, PCT, and TSGF of the research group was significantly higher than that of the control group, the differences were statistically significant （ P〈0.05 ） . Conclusion： The increased levels of CRP, PCT, and TSGF provide important reference for diagnosis and treatment of MPP, have a broader clinical significance.

关 键 词：支原体肺炎 C-反应蛋白 降钙素原 特异性生长因子 

分 类 号：R725.6[医药卫生—儿科]