组织学前列腺炎对前列腺增生患者尿动力学参数及尿潴留的影响  

The Influence of Histological Prostatitis to Urodynamic Parameters and Urinary Retention in Patients with Benign Prostatic Hyperplasia

作　　者：黄宏双[1] 郑晓娴[1] 谢锦来[1] 陈智伟[2] 晏湘山[1] 

机构地区：[1]莆田学院附属医院泌尿外科,莆田351100 [2]莆田学院附属医院病理科,莆田351100

出　　处：《福建医科大学学报》2015年第4期236-238,248,共4页Journal of Fujian Medical University

摘　　要：目的探讨合并组织学前列腺炎(HP)对前列腺增生患者的尿动力学参数及尿潴留的影响。方法回顾性分析98例接受经尿道前列腺等离子双极电切术治疗的良性前列腺增生(BPH)患者资料,根据病理诊断分为单纯BPH组和BPH合并HP组,比较国际前列腺症状评分(IPSS)、前列腺体积(PV)、前列腺特异性抗原(PSA)、最大尿流率、最大膀胱容量(MBC)、最大逼尿肌收缩力和膀胱出口梗阻指数(BOOI)等尿动力学指标及膀胱逼尿肌过度活动、尿潴留发生率间的差异。结果与单纯BPH组比较,BPH合并HP组具有更高的IPSS评分(P=0.020)和PSA值(P=0.009),更高的BOOI指数(P=0.003),较小的最大膀胱容量(P=0.004),更高的膀胱逼尿肌过度活动的发生率(P=0.041)和尿潴留发生率(P=0.010)。结论合并HP的BPH患者下尿路症状更重,血清PSA升高,导致MBC降低、膀胱出口梗阻加重和逼尿肌过度活动的发生等尿动力学参数改变,更易发生尿潴留。Objective To discuss the influence of histological prostatitis （HP） on urodynamic parameters and urinary retention in patients with benign prostatic hyperplasia （BPH）. Methods 98 patients who underwent bipolar transurethral plasmakinetic prostatectomy （TUPKP） due to BPH were retrospectively reviewed and divided into two groups, BPH group and BPH with HP group, based on pathological characteristics of tissue samples. The International prostate symptom score（IPSS）, prostate volume（PV）, PSA level and urodynamic features including maximum urine flow, maximum bladder capacity, maximum detrusor contractility and bladder outlet obstruction index（BOOI） were compared between the two groups. The occurrence rate of involuntary detrusor contractions and urinary retention were analyzed in both groups. Results Patients in BPH with HP group presented significant higher IPSS total scores （P〈0. 020）, higher PSA level（P〈0. 009）, higher bladder outlet obstruction index （P=0. 003） and lower maximum bladder capacity（P=0. 004） than the patients in BPH group. Patients in BPH with HP group showed a higher occurrence rate of involuntary detrusor contraction（P=0. 041） and urinary retention than that in the other group（P=0. 010）. Conclusion The occurrence of HP is associated with severer lower urinary tract symptoms, higher PSA level, urodynamic parameters changes such as lower maximum bladder capacity, severer bladder outlet obstruction, higher proportion of detrusor over activity and urinary retention in patients with BPH.

关 键 词：前列腺增生 前列腺炎 尿动力学 

分 类 号：R697.3[医药卫生—泌尿科学]