2型糖尿病患者血25羟维生素D水平与糖化血红蛋白的相关性研究  

Correlation Study between Serum Levels of 25-hydroxyvitamin D and Glycated Hemoglobin in Patients with Type 2 Diabetes

作　　者：万芳[1] 李文斌[1] 李梅[2] 兰浩[1] 余杰[1] 宁静[1] 冯徐俊[1] 

机构地区：[1]南昌大学附属九江医院,九江市第一人民医院,江西九江332000 [2]四川省宜宾市第二人民医院

出　　处：《中国医学创新》2015年第35期53-55,共3页Medical Innovation of China

基　　金：四川省卫生厅资助课题项目(090559);江西省九江市科学技术局2013年度第一批社会发展类科技计划基金资助项目(201303)

摘　　要：目的:探讨2型糖尿病患者血25羟维生素D水平与糖化血红蛋白的相关性。方法:选取78例2型糖尿病患者,测定其血液中25羟维生素D水平与糖化血红蛋白,根据美国内分泌学会推荐的血清25-OH-Vit D水平情况,将患者分为维生素D缺乏组(25-OH-Vit D<20 ng/m L)和维生素D非缺乏组(25-OH-Vit D≥20 ng/m L),分析探讨两组患者糖化血红蛋白的情况。结果:维生素D缺乏组的Hb A1c水平为(9.43±1.87)%,明显高于维生素D非缺乏组的(8.49±2.06)%,比较差异有统计学意义(t=2.11,P=0.04)。结论:2型糖尿病患者维生素D缺乏组Hb A1c水平明显高于非缺乏组,予以适当补充维生素D制剂,可能有助于改善2型糖尿病患者血糖水平。Objective：To investigate the relevance of serum levels of 25-hydroxyvitamin D and glycated hemoglobin in patients with type 2 diabetes.Method：78 patients with type 2 diabetes were selected and measured the serum levels of 25-hydroxyvitamin D and glycated hemoglobin,according to the American Endocrine Society recommended serum levels of 25-OH-Vit D situation,the patients were divided into the vitamin D deficiency group（25-OH-Vit D20 ng/m L） and the Vitamin D non deficient group（25-OH-Vit D ≥ 20 ng/m L）,the glycated hemoglobin level of the two groups were analyzed and discussed.Result：The glycated hemoglobin level of Vitamin D deficiency group was（9.43±1.87）%,which was significantly higher than（8.49±2.06）% of the Vitamin D non deficient group,the difference was statistically significant（t=2.11,P=0.04）.Conclusion：The Hb A1 c level of the vitamin D deficiency group in patients with type 2 diabetes is significantly higher than non deficient group.Vitamin D supplements may be appropriate to improve blood glucose levels in patients with type 2 diabetes.

关 键 词：2型糖尿病 25羟维生素D 糖化血红蛋白 

分 类 号：R587.1[医药卫生—内分泌]