内关穴位埋针对高脂血症大鼠肾脏SOD、GSH-PX、MDA影响  

Effects of Needle-embedding Therapy of Neiguan on SOD、GSH-PX and MDA in Kidney of the Hyperlipemia Rat

作　　者：欧阳娟[1] 邹晓琴[1] 蒋绍祖[1] 

机构地区：[1]赣南医学院生理学教研室,江西赣州341000

出　　处：《赣南医学院学报》2015年第6期844-845,858,共3页JOURNAL OF GANNAN MEDICAL UNIVERSITY

基　　金：国家自然科学基金(NO.31060144);江西省教育厅科学技术研究项目(GJJ09326)

摘　　要：目的:探讨内关穴位埋针对高脂血症大鼠肾脏SOD、GSH-PX、MDA作用。方法:将30只雄性SD大鼠随机分为对照组、模型组、内关组,每组10只。对照组每天给予基础饲料喂养,其余2组每天给予高脂饲料喂养。喂养2周后内关组给予穴位埋针7天,治疗结束后,检测肾脏超氧化物歧化酶(SOD)活性、谷胱甘肽过氧化物酶(GSH-PX)活性与丙二醛(MDA)含量。结果:与模型组相比,内关穴位埋针可显著升高肾脏SOD、GSH-PX的活性(P<0.05),而肾脏MDA含量明显降低(P<0.05)。结论:在高脂血症情况下,内关穴位埋针可调节肾脏SOD、GSH-PX与MDA可能与促进特定脏器的自由基代谢有关。Objective：To probe effects of needle-embedding therapy of Neiguan on SOD,GSH-PX and MDA in kidney of the hyperlipemia rat. Methods-Thirty SD rats were randomly divided into 3 groups, a control group, a model group and a Nvguan group, 10 rats in each group. The hyperlipemia rat model was prepared by feeding high fat forage. The control group were fed by basic forage each day, and the other 2 groups were fed with high fat forage each day. After the rats were fed for 2 weeks, needle was given at ＂Nvguan＂ in the rats of the Nvguan group for 7days. At the end of treatment, the SOD and GSH-PX activities and MDA contents in kidney were tested. Results：Pointing needle at Nvguan significantly increased SOD and GSH-PX activities in kidney than the control group, and significantly decreased MDA content in kidney. Conclusion：Pointing needle at Nvguan regulating SOD and GSH-PX activity and MDA content in kidney is related with promoting metabolism of free radiations in special organs.

关 键 词：穴位埋针 高脂血症 超氧化物歧化酶 谷胱甘肽过氧化物酶 丙二醛 

分 类 号：R245[医药卫生—针灸推拿学]