三溴乙醇对小鼠麻醉效果的研究  

Anesthetic Effects of Tribromoethanol on Mice

作　　者：李莉[1] 华再东[1] 任红艳[1] 毕延震[1] 刘西梅[1] 肖红卫[1] 张立苹[1] 郑新民[1] 

机构地区：[1]湖北省农业科学院畜牧兽医研究所/动物胚胎工程及分子育种湖北省重点实验室,武汉430064

出　　处：《湖北农业科学》2015年第24期6328-6329,共2页Hubei Agricultural Sciences

基　　金：国家转基因重大专项(2014ZX08006-003;2014ZX08010-3);湖北省科技支撑计划项目(2014BBB010);湖北省农业科技创新中心项目(2015-620-001-003);国家自然科学基金项目(31201790)

摘　　要：为研究三溴乙醇对小鼠的麻醉效果,使用5组不同剂量三溴乙醇（200、350、500、800和1000 mg/kg）分别腹腔注射小鼠,进行小鼠麻醉。结果表明,200 mg/kg三溴乙醇腹腔注射小鼠,麻醉效果很差,小鼠未达到麻醉状态而持续动弹,350-800 mg/kg三溴乙醇腹腔注射小鼠能达到很好的麻醉效果。To study anesthetic effects of tribromoethanol on mice, the tribromoethanol were processed intraperitoncal injection with five groups of different dose gradients （200、350、500、800 and 1 000 mg/kg） respectively, and then the anesthesia onset time and duration time were compared. Results showed that the tribromoethanon at dosage of 200 mg/kg showed the worst anesthesia effect, the mice were unanesthetized and kept moving; intraperitoncal injection of tribromoethanol at dosage of 350~800 mg/kg had moderate anesthesia duration and adequate anesthesia depth, which were suitable anesthesia for mice.

关 键 词：三溴乙醇 麻醉 小鼠 效果 

分 类 号：Q95-33[生物学—动物学]