原发性肝癌介入治疗临床疗效分析  

Analysis of Clinical Curative Effect of Primary Carcinoma of Liver Interventional Therapy

作　　者：于士龙[1] 陈健[1] 王修[1] 金刚[1] 

机构地区：[1]吉林省肿瘤医院介入科,吉林长春130012

出　　处：《中外医疗》2015年第35期83-84,共2页China & Foreign Medical Treatment

摘　　要：目的比较两种介入治疗方案对原发性肝癌的临床疗效,确定最优治疗方案,为临床治疗原发性肝癌提供依据。方法整群选取2014年7月—2015年7月该院收治的114例原发性肝癌患者,随机分为对照组57例和治疗组57例,对照组采用TACE介入治疗;治疗组采用TACE+PEI介入治疗,比较两组介入治疗方案的临床治疗效果和治疗后1年内的生存率。结果通过两组患者治疗效果比较,治疗组患者治疗总有效率为91.23%,显著高于对照组治疗总有效率为71.93%,差异比较有统计学意义(χ2=10.6,P<0.05);通过1年内患者生存情况比较,在3个月、6个月、9个月及12个月治疗组患者生存率分别为84.46%、71.93%、66.67%、59.65%,而对照组各时间段生存率分别为75.44%、66.67%、61.40%、50.88%,患者各时间段比较差异有统计学意义(P<0.05)。结论 TACE+PEI介入治疗原发性肝癌,具有创伤小、安全有效、不良反应小等优点,可以有效改善病人的生活质量延长生存期,是治疗原发性肝癌有效介入治疗方法。Objective To compare the clinical curative effect of two interventional therapy plans for primary carcinoma of liver and determine the preferred therapy plan and provide basis for treating primary carcinoma in clinic. Methods 114 cases of patients with primary carcinoma treated in our hospital from July 2014 to July 2015 were selected and randomly divided into two groups with 57 cases in each, the control group were given TACE interventional therapy, the therapy group were given TACE＋PEI interventional therapy, the clinical therapy effect of the two interventional therapy plans and the sur- vival rate after 1 year of therapy were compared. Results The total effective rate in the therapy group was obviously higher than that in the control group （91.23% vs 71.93%）,the difference was obvious （X2=10.6,P〈0.05）; the survival rate in the 3 months of treatment, 3 months of treatment, 9 months of treatment and 12 months of treatment was respectively 84.46%, 71.93%,66.67% and 59.65% in the therapy group and 75.44%,66.67%,61.40%and 50.88% in the control group, the difference in each time period was obviousl （P〈0.05）. Conclusion TACE＋PEI interventional therapy for primary carcinoma of liver has advantages of small trauma, safe and effective and small side effect and can effectively improve the patient＇s quality of life and prolong the survive period, which is an effective therapy method for treating primary carcinoma.

关 键 词：原发性肝癌 介入治疗 临床疗效 

分 类 号：R4[医药卫生—临床医学]