联合用药治疗社区获得性肺炎临床疗效探讨  

Clinical Observation of Curative Effect of Drug Combination in Treatment with Community Acquired Pneumonia

作　　者：孙英霞[1] 

机构地区：[1]吉林省人民医院呼吸科,吉林长春130021

出　　处：《中外医疗》2015年第35期105-106,共2页China & Foreign Medical Treatment

摘　　要：目的探讨联合用药在治疗社区获得性肺炎临床疗效中的应用价值。方法整群选取2013年9月—2014年9月该院收治的确诊为轻中度社区获得性肺炎患者152例作为此次研究考察对象,随机分为对照组76例和治疗组76例,对照组患者采用阿奇霉素进行治疗,治疗组患者采用阿奇霉素和莫西沙星联合治疗,通过两组患者治疗总有效率和总不良反应率比较两种治疗方法的可行性。结果根据治疗总有效率比较,对照组总有效率为77.63%,而治疗组总有效率为74.74%,比较差异有统计学意义(P<0.05);根据两组患者的不良反应比较,对照组总不良反应率为11.85%,治疗组总不良反应率为9.21%,两组间差异无统计学意义(P>0.05)。结论联合用药具有高治疗效果、高安全性的优势,值得临床推广应用。Objective To discuss the application value of clinical curative effect of drug combination in treatment of 76 cases with community acquired pneumonia. Methods 152 cases of patients with mild and moderate community acquired pneumonia confirmed in our hospital from September 2013 to September 2014 were selected as the research object and randomly divided into two groups with 76 cases in each, the control group were treated with azithromycin, the treatment group were treated with azithromycin combined with moxifloxacin, the feasibility of the two treatment methods was compared through the total treatment effective rate and total rate of adverse reaction. Results The total effective rate was 77.63% in the control group and 74.74% in the treatment group, and the difference was statistically significant by comparison （P〈0.05）; the total rate of adverse reaction was 11.85% in the control group and 9.21% in the treatment group, the difference between the two groups was not statistically significant（P〉0.05）. Conclusion Drug combination has the advantages of high treatment effect and high security, which is worthy of promotion and application in clinic.

关 键 词：社区获得性肺炎 联合用药 阿奇霉素 莫西沙星 临床疗效 

分 类 号：R4[医药卫生—临床医学]