补肾方药改善子宫内膜容受性的机制研究进展  

Mechanism Research Advancement of Reinforcing the kidney to Improving Endometrial Receptivity

作　　者：李婷婷[1] 连方[2] 

机构地区：[1]山东中医药大学第一临床学院,济南250355 [2]山东中医药大学第一附属医院中西医结合生殖与遗传中心,济南250014

出　　处：《中国中医基础医学杂志》2016年第2期293-295,共3页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：国家自然科学基金面上项目(81273790)-基于体外受精-胚胎移植卵巢颗粒细胞基因组学的肾主生殖理论研究;国家自然科学基金面上项目(81473720)-基于关键基因表达调控网络的肾主生殖理论研究;国家自然科学基金面上项目(81373676)-基于体外受精-胚胎移植卵泡液代谢组学的肾主生殖理论研究

摘　　要：近年来,关于子宫内膜容受性的研究已经成为生殖医学领域的重要组成部分。现代中医学认为"肾藏精,主生殖",在该理论的指导下,提高子宫内膜容受性的临床和实验研究多从补肾入手,并结合现代研究技术,取得了较好的疗效和实验效果。故从超声评价、组织形态学、激素受体表达、分子水平、基因水平等5个层次,就补肾改善子宫内膜容受性的机制研究进展进行综述,以期为中医药在提高子宫内膜容受性方面的应用提供依据,同时借助子宫内膜容受性的研究,揭示补肾方药的作用机理,为进一步深化中医药在生殖方面的理论研究提供基础,使中西医相互促进联合应用进一步提高临床妊娠率成为可能。In recent years, the study of endometrial receptivity has been an important part of Reproductive Medicine. Under the guidance of the theory that Shen takes charge of Reproduction which from Traditional Chinese Medicine, the clinical and experimental researches of improving endometrial receptivity are focusing on reinforcing the kidney in the combination of modern research technology, and have made satisfactory curative and experimental effect. This article summarized the mechanism research advancement of reinforcing the kidney to improving endometrial receptivity, in the hope of providing evidence for the curation of TCM to manifest its superiority , revealing the mechanism of TCM to dig the reproductive theory of TCM ,and finally raise the clinical pregnancy rate.

关 键 词：补肾 子宫内膜容受性 生殖 

分 类 号：R271.14[医药卫生—中医妇科学]