后腹腔镜去顶术和开放手术治疗单纯性肾囊肿的Meta分析  

A Meta analysis of retroperitoneal laparoscopy and open surgical treatment for renal cyst

作　　者：白耀[1] 陈雄[1] 戴元清[2] 李东杰[1] 齐观南[1] 谭新骥 张晓波[1] 

机构地区：[1]中南大学湘雅医院国际医疗部外科,长沙410008 [2]中南大学湘雅医院老年医学科,长沙410008

出　　处：《中国医师杂志》2016年第2期178-182,共5页Journal of Chinese Physician

基　　金：湖南省自然科学基金（14JJ7004）

摘　　要：目的采用Meta分析方法比较后腹腔镜去顶减压术与开放手术治疗单纯性肾囊肿的临床疗效及安全性。方法计算机检索Medline、Cochrane Library、EMbase、CNKI、万方和维普数据库，严格按照纳入和排除标准收集并筛选两种方法治疗单纯性肾囊肿的随机对照研究，检索时间均为2000年1月1日至2015年8月31日，按纳入和排除标准由两人独立进行随机临床试验（RCT）的筛选、资料数据提取和质量评价，采用RevMan5．0软件对相关的数据进行Meta分析。结果符合纳入标准的研究21篇，共2296例患者，后腹腔镜组1162例，开放手术组1134例。Meta分析显示后腹腔镜组手术时间比开放手术组短、术中出血量比开放手术组少、住院时间比开放手术组短、术后并发症比开放手术组少、术后引流管拔除时间比开放手术组早、术后肛门排气时间比开放手术组早、术后下床活动时间比开放手术组早、而术后囊肿复发率方面差异无统计学意义。结论后腹腔镜去顶减压术在处理单纯性。肾囊肿时比开放手术临床效果好、安全性高、术后并发症少。Objective To evaluate the clinical efficacy and safety of retroperitoneal laparoseopy and open surgical treatment of simple renal cyst by Meta analysis. Methods Computer l＇etrieval of MED- LINE, Cochrane Library, EMBASE, CNKi, Wanfang and VIP databases, according to the inclusion and exclusion criteria collected and screened out a randomized controlled studies on the treatment of simple renal cysts, published from January 1,2000 to August 31, 2015. Two independent authors screened out randomized clinical trials （RCTs）, extracted data, assessed quality of data, and then carried out Meta analysis by Revman 5.0 software with related data. Results Twenty one studies met the inclusion criteria with a total of 2 296 patients, including 1 162 patients of retroperitoneal laparoscopy and 1 134 cases of open operation group. Compared to the open operation group, retroperitoneal laparoseopy showed shorter operation time, less bleeding, shorter hospitalization time, and earlier postoperative drainage tube extraction time. No sig nificant difference was found in the recurrence rate of the cyst for two groups. Conclusions The clinical efficacy, safety, and complication of retroperhoneal laparoscopy in the treatment of simple renal cyst is better than the open operation.

关 键 词：腹腔镜 减压术 外科 肾肿瘤/外科学 META分析 

分 类 号：R699[医药卫生—泌尿科学]