辨体论治为基础的中医健康管理模式防治非酒精性脂肪性肝病的研究  

Study on prevention and treatment of non-alcoholic fatty liver disease by TCM health management model based on the theory of differentiation

作　　者：王国栋[1] 陈斌[2] 李红[3] 彭杰[2] 刘璇[1] 兰红勤[3] 李晓屏[4] 

机构地区：[1]湖南中医药大学研究生院,湖南长沙410208 [2]湖南中医药大学第一附属医院肝病中心 [3]湖南中医药大学第一附属医院体检科 [4]湖南中医药大学第一附属医院治未病中心

出　　处：《中西医结合肝病杂志》2016年第1期6-8,共3页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

基　　金：2014年长沙市科技局民生科技支撑奖金专项(No.k1403057-31);2014年湖南省中医药科研计划项目(No.2014154)

摘　　要：目的:观察辨体论治为基础的中医健康管理模式防治非酒精性脂肪性肝病(NAFLD)的疗效。方法:选取符合条件的中、重度NAFLD患者118例,随机分为中医健康管理组(简称管理组)和对照组,两组患者均给予饮食和运动指导的基本健康宣教,对管理组患者进行辨体和辨证论治,对照组患者采用降脂、护肝药物治疗,观察3个月后患者BMI、肝功能、血脂、血糖、脂肪衰减(CAP)、体质和证候积分的变化情况。结果:100例患者得到随访,两组均以湿热质类型为主;与治疗前比较,两组患者治疗后的BMI、ALT、TG、TC、血糖、CAP、体质积分均下降,HDL均升高,对照组患者AST下降,差异有统计学意义(P<0.01);两组治疗后比较,管理组患者BMI、AST、TG、HDL-C、血糖、体质积分均低于对照组,CAP高于对照组,但差异均无统计学意义(P>0.05),TC、ALT低于对照组,差异有统计学意义(P<0.05)。结论:辨体论治为基础的中医健康管理模式是对NAFLD患者的一种有效管理模式,能提高本病的治疗效果。Objective： To observe the effect of treating non-alcoholic fatty liver by health management mode based on the theory of dif- ferentiation. Methods： 118cases with moderate and severe non alcoholic fatty liver disease were selected.Randomly assigned to the health management group of TCM and control group. Two groups were given diet and exercise guidance of basic health mi-ssion education.Health management group were given body differentiation and syndrome differentiation of TCM treatment.The control group were only given lipid- lowering, protect liver treatment.Three months later, the changes of BMI, liver function, blood lipids, blood glucose, fat attenuation （CAP）, physical and symptom scores were observed. Results： 100 patients were followed. The main types of physical of the two groups are dampheat constitution.Comparison of the two groups before treatment, BMI, ALT, TG, TC, blood glucose, CAP, physical integration all drop and HDL increased, The difference was statistically signifycant （P〈0.01）, AST in control group also decrease significantly （P〈0.01） ; comparison the two groups after treatment, health management group BMI, AST, TG, HDL, blood glucose, physical integration were lower than the control group, CAPis higher than the control group.but there was no statistically significant difference （P〉0.05）.TC, ALT, lower than the control group, the difference was statistically significant （P〈0.05）. Conclusion： TCM health management model based onthe theory of differentiation is an effective management model for nonalcoholicfatty liver disease, it can improve the effect of treatment for this disease.

关 键 词：非酒精性脂肪性肝病 健康管理 辨体论治 

分 类 号：R259[医药卫生—中西医结合]