研发特效药械组合产品提高急性化学损伤救治水平  

Developing specific drug/device combination products improves the treatment level of the acute chemical injury

作　　者：高春生[1] 赵建[1] 杨志奎[1] 钟武[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《国际药学研究杂志》2016年第1期121-125,共5页Journal of International Pharmaceutical Research

基　　金：国家重大新药创制重大专项课题(2014ZX09J14103-10D)(2011BAI18B01)

摘　　要：为有效应对日益增多的急性化学损伤事件,化学应急医学卫勤职能正由单纯应对经典化学战剂向突发化学事故和化学恐怖袭击的应急医学处置拓展。反映在重要的防化特需药品研发上,应大力推进作用机制新、疗效好、安全性高的解毒/抗毒药物,如疑似氰化物中毒即可服用的抗氰新药羟钴胺,以及更加便捷自如的现场递药技术如针头能自动回撤隐藏、注药时限可智能提示的自动注射针等新型药械产品的研发,从而提高突发化学事件的现场处理与应急救援能力。To deal with effectively acute chemical injury events, the service ability of protective medicine against chemical weapons has being widened from dealing with traditional chemical warfare to public chemical accident or chemical terrorist attack. Fo- cusing on the important researching and developing of medicine for chemical defense use only, the novel drug/device combination products should be vigorously promoted including the new mechanism, good curative effect and high safety of detoxification drugs such as hydroxycobalamin used in the treatment of known or suspected cyanide poisoning in both adults and the pediatric population, and the convenient and quick drug delivering technologies such as auto-injectors with a retreat hidden needle and a smart remindful injec- tion, which could improve greatly the emergency medical rescue ability of chemical accidents.

关 键 词：急性化学损伤 化学应急医学 羟钴胺 药械一体 自动注射针 

分 类 号：R129[医药卫生—环境卫生学]