CirQ-life保恩素胶囊毒性研究  

Study of Cir-Q Life Baoensu Capsules on The Toxicity

作　　者：卜荣华[1] 吕文平[1] 钟海燕 张迎庆[1] 李小莉[1] 

机构地区：[1]湖北工业大学食品与制药工程学院,湖北武汉430068 [2]香港海宸科技有限公司,香港999077

出　　处：《湖北工业大学学报》2016年第1期89-93,共5页Journal of Hubei University of Technology

摘　　要：目的:观察CirQ-life保恩素胶囊的安全性。方法:采用小鼠急性毒性试验、小鼠骨髓微核试验、大鼠30d喂养等试验方法进行各项实验。结果:小鼠急性经口毒性最大耐受剂量(MTD)均大于8414mg/kg(BW),为无毒物,其对小鼠骨髓染色体无明显损伤作用。30d喂养试验表明CirQ-life保恩素胶囊各剂量组对大鼠体重、食物利用率、血液学、血液生化、脏体系及病理组织等指标与正常对照组比较,均无显著性差异。结论:在本实验剂量范围和条件下,CirQ-life保恩素胶囊属实际无毒食品,短期使用无毒副作用。The study observed the toxicological safety of Cir-Q Life Baoensu capsules, through acute toxici- ty tests, bone marrow cell micronucleus test and feeding tests of thirty days. Results are as follows. The daily maximum toxicity dose of Cir-Q Life Baoensu in mice was 8414 mg （BW） which was innocuous sub- stance. Cir-Q Life Baoensu on the bone marrow cell micronucleus test was negative. Compared with control group,the body weight, food utilization rate, full blood count, blood biochemistry, organ/body weigh rati- os, and the histopathological examination had no significant differences on the rats after thirty-day feeding. It has been proven that Cir-Q Life Baoensu capsules is actually non-toxic and may be regarded as the safe foods used in the human body.

关 键 词：急性毒性 遗传毒性 30天喂养试验 

分 类 号：TS218[轻工技术与工程—粮食、油脂及植物蛋白工程]